Table 1.
Patients characteristics with transitional cell carcinoma recurrence within an intestinal urinary diversion (TCCUD)
| Total Patients Male Female |
19 14 (73.6) 5 (26.3) |
| Age at radical cystectomy (SD) | 66.7 ±6.5 |
| ASA 2 3 Missing |
6 (31.5) 8 (15.7) 5 (26.3) |
| Neoadjuvant chemotherapy before radical cystectomy | 2 (12.5) |
| BCG before cystectomy | 9 (56.2) |
| Presence of CIS at radical cystectomy | 10 (52.6) |
| Bladder cancer multifocality | 11 (57.8) |
| pT stage Bladder pT1 pT2 pT3 PT4 CIS |
4 (21.0) 5 (26.3) 4 (21.0) 1 (5.2) 5 (26.3) |
| Type of urinary diversion Ileal conduct Neobladder |
10 (52.6) 9 (47.3) |
| pN+ at RC | 3 (15.7) |
| Negative surgical margins at radical cystectomy | 18 (94.8) |
| Adjuvant chemotherapy post radical cystectomy | 5 (26.3) |
| History of Upper tract TCC | 9/19 (47.3) |
| Site of upper tract TCC Renal pelvis only Ureter and renal pelvis Ureter alone |
2 (10.5) 5 (26.3) 2 (10.5) |
| Nephroureterectomy after RC, before diagnosis of TCCUD Nephroureterectomy after salvage surgery for TCCUD Nephroureterectomy concomitant to salvage surgery for TCCUD |
6/9 (66.6) 1/9 (11.1) 2/9 (22.2) |
| pT stage nephroureterectomy pT1 pT2 CIS |
1 (5.2) 4 (21.0) 4 (21.0) |
| Presentation Gross hematuria Urine cytology Imaging abnormalities on follow-up Fecaluria |
9 (47.3) 5 (26.3) 3 (15.7) 2 (10.5) |
| Time from radical cystectomy to urinary diversion recurrence, months (IQR) | 51.2 (15.7–111.4) |
ASA – American Society of Anesthesiologists physical status classification; IQR – interquartile range, SD – standard deviation; TCC – transitional cell carcinoma; TCCUD – transitional cell carcinoma recurrence within an intestinal urinary diversion; RC – radical cystectomy; BCG – Bacillus Calmette–Guérin; CIS – carcinoma in situ