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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Genet Med. 2019 May 31;21(11):2644–2649. doi: 10.1038/s41436-019-0551-9

Fig. 2. Hypothesized mechanisms for genome-wide paternal uniparental isodisomy (GWpUPD).

Fig. 2

Legend: each bar represents a maternal or paternal haplotype. The X or the Y next to the bar indicates the associated sex chromosome. a Androgenetic chimera. Fertilization occurs between an egg with an anuclear polar body and two sperm. Haploidy rescue occurs leading to two cell line populations with three different haplotypes. b Androgenetic chimera. Fertilization occurs between an egg and two sperm. The second sperm pronucleus partially fails to fuse. Haploidy rescue occurs leading to two cell populations with three different haplotypes. c Androgenetic chimera. Fertilization occurs between an egg and two sperm to create a triploid embryo that undergoes diploidization. This is extremely unlikely as the main mechanism of triploidy is delayed incorporation. The zygote contains three haplotypes.