Table 1.
Study first author | Ahmadi [44] | Al-Qaness [51] | Ayyoubzadeh [52] | DELPHI [10] | Ghaffarzadegan [41] | Gu (YYG) [17] | Haghdoost [27] | |
Situation of study | Published paper | Published paper | Published paper | Web site | Published paper | Web site | Full report (Farsi) | |
Epidemic start date | 20-02-19 | 20-01-22 | 20-02-11 | N/M a | 20-01-02 | 20-01-26 | 20-01-21 | |
Inputs: population | N/M a | N/M a | N/M a | Yes | Yes | Yes | Yes | |
Inputs: cases | Yes | Yes | Yes | Yes | Yes | No | No | |
Inputs: cases (source) | MOHME b official reports | World Health Organization | Worldometers website c | Johns Hopkins University d | MOHME b official reports; unofficial reports | Johns Hopkins University d | N/A e | |
Inputs: deaths | Yes | No | No | Yes | Yes | Yes | No | |
Inputs: deaths (source) | MOHME b official reports | N/A e | N/A e | Johns Hopkins University d | MOHME b official reports; unofficial reports | Johns Hopkins University d | N/A e | |
Other input data | Number of cured [recovered] cases | N/A e | N/A e | Nonpharmaceutical interventions | Number of tests, Detected infected travelers, Travel data | Case and hospitalization data f | Post-infection isolated persons, Hospitalized cases, Infected cases recovered without isolation or hospitalization | |
Output date range (number of days) | 20-02-19 to 20-04-03 (45 days) | 20-01-22 to 20-04-07 (77 days) | 20-02-11 to 20-03-18 (37 days) | 20-06-01 to 20-07-15 (45 days) | 19-12-31 to 20-06-30 (183 days) | 20-01-26 to 20-11-01 (281 days) | 20-01-21 to 20-05-20 (121 days) | |
Place | Iran | 4 countries | Iran | 148 countries | Iran | 70 countries | Iran and Tehran capital city | |
Compartmental model g | SIR g | None | None | SEIR+ g, h | SEIR+ g | SEIR g | SEIR+ g | |
Statistical method: name | 3 growth models i | 6 time-series models j | 2 Models k | Regression trees | Dynamic simulation model | Machine learning | Dynamic model | |
R0 estimation results | 1.75 | None | None | None | 2.72 (before starting the interventions) | 4 estimates k | 3 estimates l | |
Scenarios /models: number | 3 m | 1 | 1 | 1 | 6 n | 1 | 4 o | |
Other factors | No | No | No | Yes. Asymptomatic cases, under-reporting | Yes p | Yes. Asymptomatic cases, under-reporting | Yes q | |
Primary outcomes | Cumulative deaths, Cumulative cases | Cumulative cases | Normalized Daily cases | Cumulative and daily deaths and cases | Cumulative deaths, Cumulative cases, Current cases | Cumulative and daily deaths and cases, Daily prevalent cases | Cumulative and daily deaths and cases, Daily prevalent cases | |
Primary outcomes interval estimates | No | No | No | No | No | Yes | No | |
Other outcomes | None | None | None | Active, Active hospitalized, Cumulative hospitalized, Active ventilated | None | Reproduction Number | Needed hospital beds, ICU beds | |
Other outcomes interval estimates | N/A e | N/A e | N/A e | No | N/A e | Yes | No | |
Model validation | No | Yes r | Yes s | No t | Yes u | Yes v | No | |
Study limitations mentioned | Yes | Yes | Yes | Yes | Yes | Yes | No | |
Study limitations described | Yes | No | No | Yes | No | Yes | No | |
Study first author | Hsiang [45] | IHME [12] | Imperial [13] | LANL [14] | Mashayekhi [28] | Moftakhar [53] | Moghadami [36] | |
Situation of study | Published paper | Web site [12] and published paper [30] | Web site [13] and published paper [34] | Web site | Summary report (Farsi) | Published paper | medRxiv preprint | |
Epidemic start date | N/M aa | N/M aa | 20-01-03 | N/M aa | 20-02-19 [?] | 20-02-19 | 20-02-19 | |
Inputs: population | Yes | Yes | Yes | Yes | Yes | No | No | |
Inputs: cases | Yes | Yes | Yes | Yes | No | Yes | Yes | |
Inputs: cases (source) | Wikipedia bb | Johns Hopkins University cc | Johns Hopkins University cc | Johns Hopkins University cc | N/A dd | MOHME ee and Johns Hopkins cc | MOHME ee | |
Inputs: deaths | Yes | Yes | Yes | Yes | No | No | Yes | |
Inputs: deaths (source) | Wikipedia bb | Johns Hopkins University cc | Johns Hopkins University cc | Johns Hopkins University cc | N/A dd | N/A dd | MOHME ee | |
Other input data | 3 variables ff | 4 variables gg | 5 variables hh | N/M aa | N/M aa | N/M aa | None | |
Output date range (number of days) | ~ 20-02-28 to 20-04-06 (~ 39 days) | 20-02-04 to 21-02-01 (364 days) | 20-01-06 to 20-11-24 (324 days) | 20-03-14 to 20-11-07 (239 days) | N/M aa (360 days) | 20-03-21 to 20-04-20 (31 days) | 20-03-21 to 20-04-20 (31 days) | |
Place | 6 countries | 165 countries | 164 countries | 157 countries | Iran | Iran | Iran and top 5 provinces | |
Compartmental model ii | SIR+ ii | SEIR ii | SIR, SEIR, SEIR+ ii | SEIR+ ii | SLIR+ ii | None | None | |
Statistical method: name | Multiple regression | Curve fitting (backcating) functional analysis (forecasting) | Regression trees | Dynamic growth parameter modeling | Dynamic model | Autoregressive Integrated Moving Average (ARIMA) | Exponential smoothing model | |
R0 estimation results | Not used | N/M aa | N/M aa | N/M aa | Not used | Not used | Not used | |
Scenarios /models: number | 2 jj | 3 kk | 6 ll | 1 | 3 mm | 1 | 1 | |
Other factors | Yes. Under-reporting. | Yes nn | Yes. Under-reporting. | Yes. Under-reporting. | Yes oo | No | No | |
Primary outcomes | Cumulative cases | Cumulative and daily deaths and cases | Cumulative and daily deaths and cases | Cumulative and daily deaths and cases | Cumulative and daily deaths, Daily symptomatic and asymptomatic cases | Daily cases | Cumulative deaths, cases, recovered cases | |
Primary outcomes interval estimates | Yes | Yes | Yes | Yes | No | Yes | Yes | |
Other outcomes | None | Yes pp | Yes qq | None | None | None | None | |
Other outcomes interval estimates | N/A dd | Yes | Yes | N/A dd | N/A dd | N/A dd | N/A dd | |
Model validation | (?) | Yes rr | Yes ss | Yes tt | No | Yes uu | Yes vv | |
Study limitations mentioned | Yes | Yes | No | No | Yes | Yes | No | |
Study limitations described | Yes | Yes | No | No | No | Yes | No | |
Study first author | Moradi [42] | Muniz-Rodriguez [37] | Pourghasemi (PLoS ONE) [38] | Pourghasemi (IJID) [39] | Rafieenasab [54] | Rahimi Rise [29] | Saberi (web site) [21] | Saberi (paper) [22] |
Situation of study | Published paper | Published paper | Published paper | Published paper | Published paper | Published paper (Farsi) | Web site [21] | Published paper |
Epidemic start date | 20-02-20 | 20-02-19 | 20-02-25 [?] | 20-02-25 [?] | 20-02-19 | 20-02-01 | 20-02-19 | 20-02-19 |
Inputs: population | No | N/M aaa | Yes | Yes | N/M aaa | Yes | N/M aaa | Yes |
Inputs: cases | No | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
Inputs: cases (source) | N/A bbb | MOHME ccc official reports | MOHME ccc official reports | MOHME ccc official reports | MOHME ccc official reports | Worldometers website ddd | MOHME ccc official reports, WHO, Worldometers ddd | MOHME ccc official reports, WHO |
Inputs: deaths | Yes | No | Yes | Yes | No | Yes | Yes | Yes |
Inputs: deaths (source) | MOHME ccc official reports | N/A bbb | MOHME ccc official reports | MOHME ccc official reports | N/A bbb | Worldometers website ddd | MOHME ccc official reports, WHO, Worldometers ddd | MOHME ccc official reports, WHO, Worldometers ddd |
Other input data | None | Travel data | Environmental and meteorological conditions | Environmental and meteorological conditions | None | Public transportation variables | None | None |
Output date range (number of days) | 20-02-20 to 20-03-26 (36 days) | 20-02-19 to 20-02-29 (11 days) | ~ 20-02-25 to ~ 20-06-10 (~ 107 days) eee | ~ 20-02-25 to ~ 20-06-20 (~ 117 days) fff | 20-02-19 to 20-06-07 (110 days) | 20-02-01 to 20-08-01 (183 days) | 20-02-19 to 21-02-02 (350 days) | ~ 20-03-19 to 20-10-26 (~ 222 days) |
Place | Iran | Iran and 2 multi-province regions | Iran and Fars Province | Iran, 31 Provinces of Iran, World | Iran | Iran | Iran | Iran |
Compartmental model ggg | None | None | None | None | SIR+ ggg, hhh | SEIR ggg | SIR ggg | SEIR+ ggg, iii |
Statistical method: name | Calculating number of cases based on different assumptions for case fatality rate (CFR) | Generalized growth mode; Based on the calculation of the epidemic doubling times | Autoregressive Integrated Moving Average (ARIMA) and polynomial regression | Fourth-degree polynomial regression | 3-steps model based on the SIR model | Dynamic model | Classical SIRggg mathematical model with homogenous mixing assumption | Ordinary least squares minimization |
R0 estimation results | Not used | Two methods: 3.6 and 3.58 | Not used | Not used | 2.8–3.3 (range) | Not used | 2.37 (for the last 7 days before 20-03-21) | 1.73 (20-03-01) and 0.69 (2004-15) jjj |
Scenarios /models: number | 4 kkk | 2 lll | 1 | 1 | 1 | 2 | 12 mmm | 3 nnn |
Other factors | No | No | No | No | No | Yes. Asymptomatic cases | Yes ooo | Yes ppp |
Primary outcomes | Cumulative cases | Daily cases | Cumulative and daily deaths and cases qqq | Cumulative and daily deaths and cases rrr | Cumulative and daily deaths, Daily cases | Daily deaths and cases | Cumulative cases, Daily active cases | Fractions of national population estimated to be confirmed and suspected cases sss |
Primary outcomes interval estimates | No | Yes | No | No | No | No | No | Yes |
Other outcomes | Case Fatality Rate | None | None | None | None | None | None | Intensive Care Unit beds needed |
Other outcomes interval estimates | No | N/A bbb | N/A bbb | N/A bbb | N/A bbb | N/A bbb | N/A bbb | Yes |
Model validation | No | No | Yes ttt | Yes uuu | No | Yes vvv | No | Yes www |
Study limitations mentioned | Yes | Yes | No | Yes | No | No | Yes | Yes |
Study limitations described | No | Yes | No | No | No | No | No | Yes |
Study first author | Shen [43] | Singh [55] | Srivastava [15] | Thu [48] | Tuite [46] | Zhan [40] | Zhuang [47] | |
Situation of study | Published paper | Published paper | Web site [15] and preprint [35] | Published paper | Published paper | Published paper | Published paper | |
Epidemic start date | 20-02-20 | N/M aaaa | N/M aaaa | N/M aaaa | N/M aaaa | 20-02-19 | N/M aaaa | |
Inputs: population | No | No | N/M aaaa | No | N/M aaaa | N/M aaaa | Yes | |
Inputs: cases | Yes | Yes | Yes | Yes | No | Yes | No | |
Inputs: cases (source) | “WIND DATA” bbbb | Worldometers cccc | Johns Hopkins University dddd | WHO | N/A bbbb | MOHME eeee official reports | N/A ffff | |
Inputs: Deaths | No | No | Yes | Yes | No | Yes | No | |
Inputs: Deaths (source) | N/M aaaa | N/M aaaa | Johns Hopkins University dddd | WHO | N/A ffff | WHO | N/A ffff | |
Other input data | None | None | None | Social distancing | Exported cases from Iran to other countries; Travel data | COVID-19 spreading profiles of 367 cities in China | Exported cases from Iran to other countries, Travel data | |
Output date range (number of days) | 20-02-20 to 20-04-20 (61 days) | 20-04-24 to 20-07-07 (75 days) | 20-09-19 to 20-12-19 (every 7th day, 14 dates, 92 days duration) | 20-03-30 to 20-05-02 (34 days) | 20-01-01 to N/M aaaa | 20-02-22 to 20-06-24 (124 days) | 20-02-01 to 20-02-24 (24 days) | |
Place | 9 countries and 11 provinces / municipalities in China | 15 countries | 184 countries | 10 countries | Iran | Iran and 12 provinces | Iran | |
Compartmental model gggg | None | None | SIR+ gggg, hhhh | None | None | SEIR+ gggg | None | |
Statistical method: name | Logistic growth | Autoregressive Integrated Moving Average (ARIMA) | Hyper-parametric learning | Linear growth rates iiii | N/M aaaa | Data-driven prediction algorithm kkkk | Binomial distributed likelihood framework | |
R0 estimation results | Not used | Not used | 1.44 (20-03-21), 1.46 (20-03-28) | Not used | Not used | Not used | Not used | |
Scenarios /models: number | 1 | 1 | 3 llll | 1 | 6 mmmm | 1 | 5 nnnn | |
Other factors | No | No | Asymptomatic cases, under-reporting | No | No | No | No | |
Primary outcomes | Cumulative cases | Cumulative cases | Cumulative deaths and cases | Daily cases | Cumulative cases | Cumulative and daily cases | Cumulative cases | |
Primary outcomes interval estimates | No | Yes | No | No | Yes | Yes | Yes | |
Other outcomes | None | None | None | None | None | None | None | |
Other outcomes interval estimates | N/A ffff | N/A ffff | N/A ffff | N/A ffff | N/A ffff | N/A ffff | N/A ffff | |
Model validation | Yes oooo | Yes pppp | Yes qqqq | No | No | Yes jjjj | No | |
Study limitations mentioned | Yes | Yes | Yes | Yes | No | Yes | Yes | |
Study limitations described | No | Yes | Yes | Yes | No | Yes | No |
a N/M: Not Mentioned
b MOHME: Ministry of Health and Medical Education, Iran
c Worldometers Coronavirus [49]
d Johns Hopkins University, Coronavirus Resource Center ([4, 5])
e N/A: Not applicable
f “We do not use case-related data in our modeling. We do look at case and hospitalization data to help determine the bounds for our search grid, as changes in cases lead changes in deaths.” Gu (YYG) [17]
g Compartmental models: S: Susceptible, E: Exposed, I: Infected, R: Removed or Recovered, L: Latent. In any model with a + sign, there are other components for augmentation of model
h DELPHI model: The model underlying the predictions is DELPHI (Differential Equations Leads to Predictions of Hospitalizations and Infections), that is based on SEIR with augmentations for under-detection and governmental response. DELPHI [10]
i Three growth models: M1: Gompertz Differential Equation, M2: Von Bertalanffy differential growth equation, and M3: Cubic polynomial least squared errors
j Six time-series models: (1) Adaptive Neuro-Fuzzy Inference System (ANFIS) enhanced with Genetic Algorithm (GA), (2) Original Adaptive Neuro-Fuzzy Inference System (ANFIS), (3) Particle Swarm Optimizer (PSO), (4) Artificial Bee Colony (ABC), (5) hybridized of Flower Pollination Algorithm and SALP Swarm Algorithm (SSAFPA), (6) Sine-Cosine Algorithm (SCA)
h Two Models: Linear Regression, Long Short-Term Memory (LSTM)
k Four estimates: Initial R0 = 2.65. Reopen R = 1.17. Current R = 1.2. Post-mitigation R = 0.90
l Three estimates: 7.24 (at the beginning). 2.58 (after interventions). 1.82 (conditional to isolation of 50% within 3 days)
m Three scenarios based on 3 growth models: S1: Gompertz Differential Equation, S2: Von Bertalanffy differential growth equation, and S3: Cubic polynomial least squared errors
n Six scenarios based on combination of two factors: Seasonality (S), and Policy interventions (P). (1) S1P1: Seasonality conditions 1 (no effect or status quo) and Policy effect 1 (status quo contact rate). Estimates for 2020-03-19, the end of first month after the epidemic start date, are equal across the six scenarios. (2) S1P2: Seasonality conditions 1 (no effect or status quo) and Policy effect 2 (aggressive efforts to decrease contact rate by half of what it would be otherwise). (3) S2P1: Seasonality conditions 2 (moderate effect; infectivity of the virus decreases linearly from April 1st and halves by June 1st, then stays the same for the rest of the simulation) and Policy effect 1 (status quo contact rate). (4) S2P2: Seasonality conditions 2 (moderate effect; infectivity of the virus decreases linearly from April 1st and halves by June 1st, then stays the same for the rest of the simulation) and Policy effect 2 (aggressive efforts to decrease contact rate by half of what it would be otherwise). (5) S3P1: Seasonality conditions 3 (very strong mitigating effect; infectivity of the virus decreases from April 1st to a quarter of its base value by June 1st, then stays the same for the rest of the simulation) and Policy effect 1 (status quo contact rate). (6) S3P2: Seasonality conditions 3 (very strong mitigating effect; infectivity of the virus decreases from April 1st to a quarter of its base value by June 1st, then stays the same for the rest of the simulation) and Policy effect 2 (aggressive efforts to decrease contact rate by half of what it would be otherwise)
o Four scenarios: S0: Basic scenario (no intervention), only 10% isolation. S1: Worst scenario, minimum (25%) isolation. S2: Medium scenario, medium (32%) isolation. S3: Best scenario, maximum (40%) isolation
p Seven other factors included: Asymptomatic cases, Under-reporting / Completeness of reporting cases and deaths to MOHME, Delays in reporting cases and deaths to MOHME, Testing availability, Number of tests performed, Social distancing / Quarantine interventions, Seasonality
q Two other factors included: Seasonality, Social distancing / Quarantine interventions
r Root Mean Squared Error (RMSE), Mean Absolute Error (MAE), Mean Absolute Percentage Error (MAPE), Root Mean Squared Relative Error (RMSRE), and Coefficient of Determination (R square)
s Root Mean Squared Error (RMSE)
t Friedman [31] assessed predictive performance of international COVID-19 mortality forecasting models, using median absolute percent error (MAPE) and Median absolute errors (MAE)
u Root Mean Squared Error (RMSE)
v Mean Square Error (MSE), Mean Absolute Error (MAE), and Ratio Error (RE). Did not mention the results
aa N/M: Not Mentioned
bb Wikipedia. COVID-19 pandemic in Iran [56]
cc Johns Hopkins University, Coronavirus Resource Center ([4, 5])
dd N/A: Not Applicable
ee MOHME: Ministry of Health and Medical Education, Iran
ff Four variables: Cumulative recoveries, Active cases, Any changes to domestic COVID-19-testing regimes, such as case definitions or testing methodology, and Non-pharmaceutical interventions
gg Three variables: Mobility, Testing, and Seroprevalence (the latter for 41 locations)
hh Five variables: Interventions, Social contacts, Comorbidities, Hospital bed capacity, Intensive Care Unit bed capacity
ii Compartmental models: S: Susceptible, E: Exposed, I: Infected, R: Removed or Recovered, L: Latent. In any model with a + sign, there are other components for augmentation of model
jj Two scenarios: ‘No-policy scenario’ and ‘Actual policies’
kk Three scenarios: S1 Best (Masks): ‘Universal Masks’ scenario reflects 95% mask usage in public in every location. S2 Reference (Current): ‘Current projection’ scenario assumes social distancing mandates are re-imposed for 6 weeks whenever daily deaths reach 8 per million (0.8 per 100,000). S3 Worse (Easing): ‘Mandates easing’ scenario reflects continued easing of social distancing mandates, and mandates are not re-imposed
ll Six scenarios: S1: Additional 50% Reduction. S2: Maintain Status Quo. S3: Relax Interventions 50%. S4: Surged Additional 50% Reduction. S5: Surged Maintain Status Quo. S6: Surged Relax Interventions 50%
mm S1: Ideal scenario, serious distancing. People reduce their social [physical] contacts to 20% of regular level, voluntarily or on a forced basis, after number of cases and deaths have increased, plus close observation of sanitation cautions, so that transmission rate reduces by 65%. S2: Medium scenario, not serious distancing. People reduce their social [physical] contacts only to 20% of regular level, voluntarily, after number of cases and deaths have increased, and other settings are like scenario 1. S3: Worst scenario. People reduce their social [physical] contacts only to 50% of regular level, voluntarily, after number of cases and deaths have increased, plus inadequate observation of sanitation cautions, so that transmission rate reduces only by 40% (instead of 55%), and 60% of people do not observe the sanitation cautions
nn Five other factors included: Asymptomatic cases, Mobility, Testing, Seroprevalence, Seasonality
oo Two other factors included: Asymptomatic cases, Social distancing / Quarantine interventions
pp Six other outcomes: All beds needed, Intensive Care Unit beds needed, Invasive ventilators needed, Tests, Mobility, Seroprevalence
qq Five other outcomes: Hospital demand, Hospital incidence, Intensive Care Unit demand, Intensive Care Unit incidence, Rt (Effective Reproduction Number)
rr IHME web site [12] refers to Friedman [31], who assessed predictive performance of international COVID-19 mortality forecasting models, using median absolute percent error (MAPE) and Median absolute errors (MAE)
ss Mean Absolute Percentage Error (MAPE)
tt They validated the model “by looking at the coverage of the forecasts, i.e. the proportion of times that the number of confirmed cases/deaths fell within a specified lower and upper bound, X min and X max. Coverage plots can help visualize how well the model is doing”
uu Graphical residual assessment of the model
vv Mean Squared Error (MSE), Root Mean Squared Error (RMSE), Mean Absolute Error (MEA), Mean Absolute Percentage Error (MAPE), Akaike Information Criterion (AIC)
aaa N/M: Not Mentioned
bbb N/A: Not Applicable
ccc MOHME: Ministry of Health and Medical Education, Iran
ddd Worldometers Coronavirus [49]
eee Start and end dates mentioned in manuscript text, mentioned in title of their Fig. 14, and shown within their Fig. 14 do not seem to be congruent
fff Start and end dates mentioned in manuscript text, mentioned in title of their Fig. 15, and shown within their Fig. 15 do not seem to be congruent
ggg Compartmental models: S: Susceptible, E: Exposed, I: Infected, R: Removed or Recovered, L: Latent. In any model with a + sign, there are other components for augmentation of model
hhh SIR with exact and approximated solutions, extrapolation based on least squares model with three functions
iii SEIR+ Distinguishing between fatal and recovered cases combined with an estimate of the percentage of symptomatic cases using delay-adjusted Case Fatality Rate
jjj Estimated effective reproduction number that ranged from 0.66 to 1.73 between February and April 2020, with a median of 1.16. Estimated a reduction in the effective reproduction number during this period, from 1.73 (95% CI 1.60–1.87) on 1 March 2020 to 0.69 (95% CI 0.68–0.70) on 15 April 2020, due to various non-pharmaceutical interventions
kkk Four scenarios based on different values of Case Fatality Rate. S1: 0.3%, S2: 0.5%, S3: 1%, and S4: 2%
lll Based on two different methods to estimate R0
mmm (1) S1P10: Scenario 1 (Best scenario, based on official reports with correction factor of 1) with 10 million susceptible population. (2) 12 scenarios based on combination of three options for number of cases and deaths to start with, and four options for the susceptible population size. (1) S1P10: Scenario 1 (Best scenario, based on official reports with correction factor of 1) with 10 million susceptible population. (2) S1P30:Scenario 1 (Best scenario, based on official reports with correction factor of 1) with 30 million susceptible population. (3) S1P50: Scenario 1 (Best scenario, based on official reports with correction factor of 1) with 50 million susceptible population. (4) S1P80: Scenario 1 (Best scenario, based on official reports with correction factor of 1) with 80 million susceptible population. (5) S2P10: Scenario 2 (Medium scenario, based on official reports with correction factor of 5 (after Dr. Rick Brennan, Director of Emergency Operations, World Health Organization [57]) with 10 million susceptible population. (6) S2P30: Scenario 2 (Medium scenario, based on official reports with correction factor of 5 (after Dr. Rick Brennan, Director of Emergency Operations, World Health Organization [57]) with 30 million susceptible population. (7) S2P50: Scenario 2 (Medium scenario, based on official reports with correction factor of 5 (after Dr. Rick Brennan, Director of Emergency Operations, World Health Organization [57]) with 50 million susceptible population. (8) S2P80: Scenario 2 (Medium scenario, based on official reports with correction factor of 5 (after Dr. Rick Brennan, Director of Emergency Operations, World Health Organization [57]) with 80 million susceptible population. (9) S3P10: Scenario 3 (Worst scenario, based on official reports with correction factor of 10 (after Russell [58]) with 80 million susceptible population. (10) S3P30: Scenario 3 (Worst scenario, based on official reports with correction factor of 10 (after Russell [58]) with 30 million susceptible population. (11) S3P50: Scenario 3 (Worst scenario, based on official reports with correction factor of 10 (after Russell [58]) with 50 million susceptible population. (12) S3P80: Scenario 3 (Worst scenario, based on official reports with correction factor of 10 (after Russell [58]) with 10 million susceptible population
nnn Three scenarios: (1) maintaining the same level of control measures as of 12 April 2020, (2) reinforcing the control measures to increase physical distancing by a 20% increase in the reproduction number, and (3) partial lifting the restrictions to ease physical distancing by a 20% decrease in the reproduction number
ooo Completeness of reporting cases and deaths to MOHME
ppp Accounted for the under-reporting of the number of infected cases using delay-adjusted case fatality ratio (CFR) approach
qqq Cumulative deaths and cases (for Iran and Fars Province), Daily deaths and cases (for Fars Province)
rrr Cumulative deaths and cases (for Iran and World), Daily or cumulative cases in 30 days after the first day of infected cases in the 31 Iranian provinces)
sss We transformed their reported fractions of national population estimated to be confirmed and suspected cases to numbers of people estimated to be confirmed and suspected cases, using a total national population of 84,297,880 (used by IHME [12])
ttt Area Under Curve (AUC)
uuu Area Under Curve (AUC)
vvv Root Mean Squared Error (RMSE)
www Root Mean Squared Error (RMSE)
aaaa N/M: Not mentioned
bbbb Mentioned: “WIND DATA, a leading financial data services provider in China”
cccc Worldometers Coronavirus [49].
dddd Johns Hopkins University, Coronavirus Resource Center ([4, 5])
eeee MOHME: Ministry of Health and Medical Education, Iran
ffff N/A: Not Applicable
gggg SEIR+ Distinguishing between fatal and recovered cases combined with an estimate of the percentage of symptomatic cases using delay-adjusted Case Fatality Rate
hhhh SI-kJ alpha model: S: Susceptible. I: Infected. k: k sub-states of infection. J: J is a hyperparameter introduced for a smoothing effect to deal with noisy data. Alpha: an additional hyperparameter to minimizes the Root Mean Squared Error
iiii They have not named their method. It could be names as linear growth rates, according to their Eq. (1) and Eq. (2)
j Another study by Zhan and colleagues was cited for validity of their models
kkkk A data-driven prediction algorithm to find the most resembling growth curve from the historical profiles in China
llll Three scenarios: Current, Released, Restricted, each with 6 levels of putative under-ascertainment parameter
mmmm Six scenarios based on six sets of international travel destinations
nnnn Five scenarios based on selected combinations of (1) Effective catchment population, (2) Detection window 10 or 8 days, and (3) 90% or 70% load factors
oooo R Square
pppp Akaike Information Criterion (AIC)
qqqq Root Mean Squared Error (RMSE)