Table 2.
Demographic, clinical, laboratory and radiological characteristics of 33 hospitalized young adults with COViD-19 considered in this study
| Characteristics | No ICU care (n = 27) | ICU care (n = 6) | p value |
|---|---|---|---|
| Mean age ± SD – years | 45.48 ± 5.09 | 42.5 ± 8.26 | 0.257 |
| Male gender – no. (%) | 16 (59.3%) | 3 (50%) | > 0.999 |
| Healthcare worker – no. (%) | 2 (7.4% | 0 | > 0.999 |
| Mean BMI ± SD | 28.7 ± 4.8 | 28.6 ± 2.84 | 0.989 |
| Smoking habit – no. (%) | 1 (4%) | 1 (33.3%) | 0.206 |
| Coexisting conditions | |||
| Hypertension | 3 (11%) | 0 | > 0.999 |
| Diabetes | 2 (7.4%) | 0 | > 0.999 |
| Chronic liver disease | 1 (3.7%) | 0 | > 0.999 |
| Neurological disease and mental disorder | 1 (3.7%) | 3 (50%) | 0.014 |
| Thyroid diseases | 0 | 1 (16.7%) | 0.182 |
| Signs and symptoms at the onset | |||
| Fever | 100% | 100% | – |
| Cough | 21 (77.8%) | 2 (33.3%) | 0.053 |
| Dyspnoea | 13 (48.1%) | 4 (66.7%) | 0.656 |
| Chest pain | 6 (22.2%) | 0 | 0.563 |
| Fatigue | 5 (18.5%) | 0 | 0.556 |
| Anosmia | 3 (11.1%) | 0 | > 0.999 |
| Diarrhoea | 6 (22.2%) | 1 (16.7%) | > 0.999 |
| Vomiting | 1 (3.7%) | 0 | > 0.999 |
| Headache | 1 (3.7%) | 1 (16.7%) | 0.335 |
| Myalgia | 4 (14.8%) | 0 | > 0.999 |
| Syncope | 6 (22.2%) | 1 (16.7%) | 0.335 |
| Respiratory distress syndrome | 6 (22.2%) | 6 (100%) | 0.001 |
| Vital signs | |||
| Systolic blood pressure. mm Hg | 132 ± 18.1 | 131 ± 20 | 0.895 |
| Heart rate | 93.3 ± 16.3 | 103 ± 3.51 | 0.291 |
| Laboratory findings | |||
| White blood cell count, ×109/L (normal range 4–11) | 6.437 ± 2.981 | 5.511 ± 2.714 | 0.492 |
| Lymphocyte count, ×109/L (normal range 1–4) | 1.091 ± 0.460 | 1.183 ± 1.051 | 0.739 |
| Platelet count, × 109/L (normal range 150–400) | 199(144.750–260.500) | 156.5 (138.750–181.750) | 0.308 |
| Alanine aminotransferase, U/L (normal range 0–35) | 39 (30.2–52) | 25 (17.5–28.7) | 0.055 |
| Aspartate aminotransferase, U/L (normal range 0–35) | 43 (28.5–49.7) | 35 (30.7–67) | 0.906 |
| Creatinine, mg/dl (normal range 0.67–1.17) | 0.86 ± 0.218 | 1 ± 0.294 | 0.093 |
| Potassium, mEq/L (normal range 3.5–5.1) | 4.1 ± 0.332 | 3.7 ± 0.460 | 0.028 |
| Lactate dehydrogenase, U/L (normal range 0–247) | 297 (255–365) | 483 (362–729) | 0.141 |
| C-reactive protein mg/mL (normal range 0–0.49) | 6.5 (2.55–11.25) | 11.7 (11.1–14.1) | 0.097 |
| Involvement on chest radiographs | |||
| No involvement | 1 (3.7%) | 0 (0%) | 0.865 |
| Ground-glass opacity | 4 (14.8%) | 1 (16.7%) | |
| Bilateral lung patch shadow | 20 (74.1%) | 5 (83.3%) | |
| Focal lesions | 2 (7.4%) | 0 (0%) | |
Data are expressed as mean ± SD, median (IQR) or n (%)
p values indicate differences between out and in-patients. P < .05 was considered statistically significant
In brackets are expressed percentages and IQR