Table 2.

Summary of demographics and sampling characteristics.

n	8
Birth weight (kg) #	0.78 (0.517 - 1.13)
gestational age (weeks) #	25.3 (23.9 - 27.7)
postnatal age (weeks) #	8.7 (3.9-23.1)
postmenstrual age (weeks) #	34.4 (30.2 – 48.1)
females (%)	5 (62.5)
plasma sample per patient #+	5 (2-18)
CSF samples per patient#	7.5 (4-16)
plasma concentrations (mg/L) #	8.6 (2.2-26.6)
CSF concentrations (mg/L) #	24.9 (2.5-230.7)
plasma time after dose (h) #	5.59 (0-14)
CSF time after dose (h) #	7.39 (0.02-57.37)
creatinine (µmol/L) #	25 (16-47)
C-reactive protein (mg/L) #	7.5 (0.5-125)
CSF protein (g/L) #	3.97 (0.62-24.34)
ventricular index (mm) #	17.3 (14.1-34.6)

Note: CSF is cerebrospinal fluid, # is median (range), + indicates median for 5/8 patients who received concomitant IV vancomycin.