. 2021 Jan 20;65(2):e01995-20. doi: 10.1128/AAC.01995-20

TABLE 3.

Prophylactic activity of cycleanine in Plasmodium berghei infection of mice

Treatment	Dose (mg/kg) per day	Parasitemia level after infection for 72 h (%)^a	Suppression of parasitemia level after infection for 72 h (%)^a	MST (days)^a
Untreated control		20.3 ± 0.8		12.7 ± 0.3
Cycleanine	25	11.5 ± 0.9^b	43.4	23.0 ± 0.6^b
Cycleanine	50	8.3 ± 1.0^b	59.0	24.5 ± 0.6^b
Pyrimethamine	1.2	4.8 ± 1.1^b	76.2	29.8 ± 0.2^b

Values are expressed as mean ± SEM (n = 6 in each group).

Significant relative to control; P < 0.001.