TABLE 4.
Accepted range of MICs and disc inhibition zone diameters for cefiderocol against quality control organisms E. coli and P. aeruginosa and respective non-species-specific breakpoints
| Organism | MIC (mg/liter) |
Zone diameter (mm) |
||||
|---|---|---|---|---|---|---|
| CLSI |
EUCAST |
CLSI | EUCAST | |||
| Range | Break pointa | Range | Break pointb | |||
| E. coli ATCC 25922 | 0.06–0.5 | 0.06–0.5 | 25–31 | 24–30 | ||
| P. aeruginosa ATCC 27853 | 0.06–0.5 | 0.06–0.5 | 22–31 | 22–28 | ||
| Non-species specific | ||||||
| Susceptible | ≤4 | ≤2 | ||||
| Resistant | ≥16 | >2 | ||||
a
CLSI breakpoints set for Enterobacterales, P. aeruginosa, A. baumannii, and S. maltophilia.
b
EUCAST PK/PD, Enterobacterales and P. aeruginosa breakpoints.