TABLE 1.
Staphylococcus epidermidis PJI and clinical isolates used in this study with associated rifamycin MICa
| Isolate name | Source (reference no.) | Rifamycin MIC (μg/ml) with: |
||
|---|---|---|---|---|
| Rifampin | Rifapentine | Rifabutin | ||
| SE1457 | Venous catheter (14) | ≤0.015 | ≤0.015 | ≤0.015 |
| IDRL-8864 | Shoulder PJI | ≤0.015 | ≤0.015 | ≤0.015 |
| IDRL-8933 | Knee PJI | ≤0.015 | ≤0.015 | ≤0.015 |
| IDRL-9950 | Elbow PJI | 1 | 4 | 0.25 |
| IDRL-6515 | Knee PJI | >128 | >128 | >128 |
| RP62A | Catheter sepsis | ≤0.015 | ≤0.015 | ≤0.015 |
| RP62A-ΔrpoB | Rat exptl osteomyelitis (15) | >128 | >128 | >128 |
a
PJI, periprosthetic joint infection; exptl, experimental.