TABLE 7.
Treatment details for the pediatric cohort
| Treatment parameter | Result for patients in age groupa |
|||||
|---|---|---|---|---|---|---|
| 0–7 mo (n = 56) | 8 mo–1 yr (n = 43) | 2–6 yr (n = 44) | 7–11 yr (n = 37) | 12–17 yr (n = 35) | Total (n = 215) | |
| Treatment complete | ||||||
| Yes | 53 (94.6) | 41 (95.3) | 41 (93.2) | 35 (94.6) | 29 (82.9) | 199 (92.6) |
| No | 3 (5.4) | 2 (4.7) | 3 (6.8) | 2 (5.4) | 6 (17.1) | 16 (7.4) |
| Treatment discontinued | ||||||
| Patient decision | 1 (2.3) | 2 (4.5) | 1 (2.7) | 2 (5.7) | 6 (2.8) | |
| Adverse event | 1 (2.3) | 1 (2.3) | 0 (0) | 2 (5.7) | 4 (1.9) | |
| Death | 1 (1.8) | 1 (0.5) | ||||
| Lost to follow-up | 2 (3.6) | 1 (2.7) | 2 (5.7) | 5 (2.3) | ||
| Temporary interruption | ||||||
| Yes | 2 (3.6) | 1 (2.3) | 2 (4.5) | 1 (2.7) | 4 (11.4) | 10 (4.7) |
| No | 54 (96.4) | 42 (97.7) | 42 (95.5) | 36 (97.3) | 31 (88.6) | 205 (95.3) |
| Compliance | ||||||
| Yes | 48 (90.6) | 37 (90.2) | 29 (70.7) | 27 (73.0) | 25 (71.4) | 166 (83.4) |
| No | 5 (9.4) | 4 (9.8 | 12 (29.3) | 12 (27.0) | 10 (28.6) | 33 (16.6) |
| Adverse events | ||||||
| Yes | 14 (25.0) | 14 (32.6) | 17 (38.6) | 11 (29.7) | 7 (20.0) | 63 (29.3) |
| No | 42 (75.0) | 29 (67.4) | 27 (61.4) | 26 (70.3) | 28 (80.0) | 152 (70.7) |
| No. of events per patient [median (Q1, Q3)] | 1.0 (1.0, 1.00) | 1.0 (1.0, 1.0) | 1.0 (1.0, 2.0) | 1.0 (1.00, 1.0) | 2.0 (1.0, 2.0) | 1.0 (1.0, 1.5) |
a
All results are numbers (percentages) of patients, except for the last row, which is number of events.