TABLE 3.
Bacterial susceptibilities to antibiotics at a low inoculum of 1 × 103 CFU/well
| Strain | MIC (μg/ml)a |
|||
|---|---|---|---|---|
| Amikacin | Gentamicin | Tobramycin | Neomycin | |
| PAK | 1.25 | 1.25 | 0.625 | 6.25 |
| ΔKH-S1 | 2.5 | 2.5 | 1.25 | 25 |
| ΔKH-S1/Tn7T-pnp | 1.25 | — | 0.625 | 12.5 |
| PAK ΔmexZ | 2.5 | 2.5 | ND | ND |
| ΔKH-S1 ΔmexZ | 2.5 | 2.5 | ND | ND |
| PAK ΔmexXY | 0.3125 | 0.3125 | ND | ND |
| ΔKH-S1 ΔmexXY | 0.3125 | 0.3125 | ND | ND |
| PAK ΔarmZ | 0.3125 | 0.3125 | ND | ND |
| ΔKH-S1 ΔarmZ | 0.3125 | 0.3125 | ND | ND |
a
“—” indicates that the complemented strain is resistant to gentamicin due to the mini-Tn7T insertion. ND, not determined.