表 3.
影像MPM患者预后的单因素和多因素分析结果
Univariate and multivariate survival analysis of prognostic factors in MPM patients
| Characteristics | 5-yr OS rate (%) | Univariate analysis | Multivariate analysis | |||
| HR(95%CI) | P | HR(95%CI) | P | |||
| Age (yr) | 0.094 (0.031-0.283) | < 0.001 | 0.320 (0.059-1.743) | 0.188 | ||
| < 65 | 40.0 | |||||
| ≥65 | 39.1 | |||||
| Gender | 0.594 (0.295-1.196) | 0.145 | 0.421 (0.193-1.862) | 0.443 | ||
| Male | 30.0 | |||||
| Female | 44.7 | |||||
| Smoking history | 2.186 (1.004-4.759) | 0.049 | 1.694 (0.671-4.274) | 0.265 | ||
| Non-smoking | 41.7 | |||||
| Smoking | 30.0 | |||||
| Histological type | 1.585 (0.649-3.970) | 0.312 | 1.392 (0.463-5.180) | 0.739 | ||
| Adenocarcinoma | 35.4 | |||||
| Squamous cell carcinoma | 28.6 | |||||
| Others | 66.7 | |||||
| Stage for lung cancer | 4.986 (2.916-8.527) | < 0.001 | 4.427 (2.456-7.979) | < 0.001 | ||
| Ⅰ | 70.8 | |||||
| Ⅱ | 26.7 | |||||
| Ⅲ | 5.3 | |||||
| EGFR mutation | 0.461 (0.223-0.954) | 0.037 | 0.385 (0.146-1.016) | 0.045 | ||
| Mutant | 46.4 | |||||
| Wild-type | 33.3 | |||||
| Operation selection | 1.367 (0.793-3.021) | < 0.001 | 1.781 (1.004-2.157) | < 0.001 | ||
| Video-assisted thoracic surgery | 43.8 | |||||
| Traditional thoracotomy | 20.0 | |||||
| Other cancers status | 3.932 (1.786-8.657) | 0.001 | 3.484 (1.458-8.321) | 0.005 | ||
| Curative | 45.5 | |||||
| Palliative | 21.4 | |||||
| Time of occurrence | 0.243 (0.112-0.524) | < 0.001 | 0.267 (0.083-0.865) | 0.028 | ||
| Synchronous | 20.0 | |||||
| Metachronous | 46.5 | |||||
| Order of occurrence | 0.461 (0.216-0.988) | 0.046 | 0.751 (0.170-3.314) | 0.016 | ||
| LCF | 23.1 | |||||
| OCF | 44.4 | |||||