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Accumulated excretion recovery ratio of jaktinib and metabolites in urine and feces.
| PK parameter | Jaktinib (n = 6) | ZG0244 (n = 6) | ZG0245 (n = 6) | ZG0243 (n = 6) | ZG0262 (n = 6) | Total |
|---|---|---|---|---|---|---|
| Urine-Fe0–120h, geometric mean (%) | 0.132 | 3.996 | — | — | — | 4.128 |
| Feces-Fe0–120h, geometric mean (%) | 12.681 | 0.395 | 1.000 | 1.072 | 0.202 | 15.350 |
| Total (%) | 12.813 | 4.391 | 1.000 | 1.072 | 0.202 | 19.478 |
Fe0–120h, accumulated excretion recovery ratio from time zero to 120 h.
