TABLE 2.

Correlation Between ADC (by Region) and US RI Without Pressure for Neonates With ADC Measured at DOL 9 or earlier

	Unadjusted Association		Adjusted Association*
Brain Region	β (est) 95% CI	P	β (est) 95% CI	P
Right ACS	0.054† (0.012–0.096)	0.015	0.053† (0.004, 0.103)	0.039
Left ACS	0.074† (0.026–0.122)	0.004	0.072† (0.016, 0.128)	0.015
Right PCS	0.062† (0.020–0.103)	0.005	0.060† (0.012, 0.108)	0.018
Left PCS	0.049† (0.014–0.084)	0.008	0.049† (0.008, 0.090)	0.022
Right basal ganglia	0.033† (0.003–0.064)	0.037	0.038† (0.003, 0.073)	0.039
Left basal ganglia	0.026 (−0.007 to 0.059)	0.126	0.038† (0.001, 0.075)	0.048
Right thalamus	0.037† (0.013–0.062)	0.004	0.040†(0.014, 0.065)	0.004
Left thalamus	0.037† (0.010–0.063)	0.009	0.044† (0.016, 0.073)	0.004
Right PLIC	0.040† (0.018–0.063)	0.001	0.040† (0.014, 0.066)	0.004
Left PLIC	0.037† (0.014–0.059)	0.002	0.045† (0.020, 0.069)	0.001
Pons	0.016 (−0.002 to 0.035)	0.094	0.017 (−0.005, 0.039)	0.145
Cerebellar white matter	0.014 (−0.007 to 0.035)	0.192	0.015 (−0.008, 0.039)	0.200

^*Adjusted for presence of PPHN, days of ventilator support, use of inotropes, and presence of a significant PDA.

^†P < 0.05.

β is the expected change in ADC for a 0.1 unit increase in RI.