Skip to main content
. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: FASEB J. 2020 Feb 28;34(4):5401–5419. doi: 10.1096/fj.201902961R

FIGURE 4.

FIGURE 4

Age-related changes in ERGs of RodΔBsg retina highlights importance of lactate transporters on rod photoreceptor function. A, Representative dark-adapted ERGs (left) and summary luminance-response functions from control and RodΔBsg littermates at 17 weeks of age. Values to the left of each pair of waveforms indicates flash strength in log cd s/m2. Calibration indicates 500 µV and 100 ms. B, Values of Rmax and RmP3 from control and RodΔBsg littermates at the ages indicated. C, Comparison of the leading edge of the a-wave of 4-week-old mice. For each mouse, amplitude was normalized to the a-wave trough. D, Values of A from control and RodΔBsg littermates at the ages indicated. E, Representative light-adapted ERGs (left) and summary luminance-response functions from control and RodΔBsg littermates at 17 weeks of age. Values to the left of each pair of waveforms indicates flash strength in log cd s/m2. Calibration indicates 100 µV and 100 ms. F, Values of Rmax for the cone ERG at the ages indicated. Data points indicate average (±SEM) for 4–7 mice