The protein interaction network of the four chemosensory pathways of P. aeruginosa. The pathway output is highlighted by boxes. The color code of signaling proteins corresponds to that of Fig. 1. CheA/WspE/ChpA, histidine kinase; CheR/WspC/PilK, methyltransferase; CheB/WspF/ChpB, methylesterase; CheW/WspB/WspD/PilI/ChpC, CheW-type coupling protein; CheV, CheV-type coupling protein; CheY/WspR/PilG/PilH, CheY-type response regulator.