Figure 4.

Effects of acute exposure to high altitude. Individual serum concentrations and means ± standard deviations of erythropoietin (n=21) (A), erythroferrone (ln transformed, n=21) (B), transferrin saturation (n=22) (C), hepcidin (ln transformed, n=7) (D) and ferritin (n=22) (E), at sea level and after 15 h of exposure to high altitude (3800 m). Of note, out of 22 subjects, 15 subjects had sea-level hepcidin concentrations which were below the detection limit; therefore, the hepcidin statistical analysis was performed on seven subjects. P values denote differences between sea level and high altitude. Epo: erythropoietin; ERFE: erythroferrone.