Table 4.
Study | Mean SpO2 (%) | Minimal SpO2 (%) | ODI (≥3%) | PaO2 and PaCO2 (mm Hg)* | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Pain:Opioids | Pain:No Opioids | No Pain:No Opioids | Pain:Opioids | Pain:No Opioids | No Pain:No Opioids | Pain:Opioids | Pain:No Opioids | No Pain:No Opioids | Pain:Opioids | Pain:No Opioids | No Pain:No Opioids | |
Recruitment location: sleep clinics | ||||||||||||
Walker 2007 | Awake: 91 ± 3,† NREM: 90 ± 3,† REM: 89 ± 7 | ― | Awake: 93 ± 2, NREM: 92 ± 2, REM: 91 ± 4 | NR | ― | NR | NR | ― | NR | ― | ― | ― |
Farney 2008 | 90 ± 4 | ― | ― | 80 ± 8 | ― | ― | 31 ± 34 | ― | ― | ― | ― | ― |
Farney 2008 | NR | NR | NR | 84 ± 6 | 83 ± 7 | 83 ± 7 | 20 ± 24 | 24 ± 27 | 25 ± 23 | ― | ― | ― |
Jungquist 2012 | 94 ± 3 | ― | ― | 83 ± 8 | ― | ― | NR | ― | ― | PaO2: 80; range, 59–99; PaCO2: range, 42–53 | ― | ― |
Recruitment location: pain clinics | ||||||||||||
Webster 2008 | NR | ― | ― | NR | ― | ― | NR | ― | ― | ― | ― | ― |
Mogri 2009 | NR | ― | ― | NR | ― | ― | NR | ― | ― | ― | ― | ― |
Rose 2014 | Awake: 94 ± 1.6† | ― | Awake: 97 ± 1.3 | NR | ― | ― | NR | ― | ― | PaO2: 81.4 ± 9; range, 74–86; PaCO2: 44.8 ± 41; range: 42–47 | ― | ― |
Shapiro 2015 | 93 ± 3 | ― | ― | 80 ± 8 | ― | ― | 33 ± 29 | ― | ― | ― | ― | ― |
Pampati 2016 | NR | NR | ― | NR | NR | ― | NR | NR | ― | ― | ― | ― |
Values are expressed as mean ± SD where appropriate. *Data obtained from arterial blood gas analysis. †P < .05 vs no pain:no opioids. NR = not reported, NREM = non–rapid eye movement, ODI = oxygen desaturation index, PaCO2 = partial pressure of CO2 in arterial blood, PaO2 = partial pressure of O2 in arterial blood, REM = rapid eye movement, SpO2 = peripheral capillary O2 saturation.