Table 1.
Clinical characteristics in participants with mild OSA and nonapneic snorers.
| Total Population (N = 4,732) | Total Population According to AHI | ||||
|---|---|---|---|---|---|
| Nonapneic Snorers (AHI < 5 events/h) (n = 2,063) | Patients with MildAHI 5-<11/h OSA (AHI, 5 to <11 events/h) (n = 1,734) | Patients with MildAHI 11-<15/h OSA (AHI, 11 to ≤15 events/h) (n = 935) | P Across All | ||
| Demographics | |||||
| Sex, males | 2,579 (55%) | 996 (48%) | 991 (57%)b | 592 (63%)a,c | <.001 |
| Age (y) | 52.4 ± 12.5 | 49.5 ± 13.0 | 54.3 ± 11.8b | 55.5 ± 11.2a,c | <.001 |
| Age ≥ 60 y | 1,448 (31%) | 492 (24%) | 592 (34%)b | 364 (39%)a,c | <.001 |
| BMI (kg/m2) | 29.8 ± 6.1 | 28.9 ± 5.8 | 30.4 ± 6.3b | 30.5 ± 6.0a | <.001 |
| BMI ≥ 30 kg/m2 | 1976 (42%) | 744 (36%) | 789 (46%)b | 443 (48%)a | <.001 |
| NC (cm) | 39.4 ± 4.2 | 38.6 ± 4.1 | 39.9 ± 4.1b | 40.4 ± 4.0a,c | <.001 |
| WC (cm) | 102.6 ± 14.7 | 99.8 ± 14.8 | 104.6 ± 14.5b | 105.4 ± 13.7a | <.001 |
| HC (cm) | 108.2 ± 12.1 | 107.1 ± 11.9 | 109.3 ± 12.6b | 108.7 ± 11.7a | <.001 |
| Waist-to-hip ratio | 0.95 ± 0.09 | 0.93 ± 0.09 | 0.96 ± 0.08b | 0.97 ± 0.08a,c | <.001 |
| Smoking status | |||||
| Never | 3,641 (77%) | 1,550 (75%) | 1,337 (88%) | 754 (81%)a,c | |
| Current/former | 1,069 (23%) | 511 (25%) | 384 (22%) | 174 (19%)a,c | .001 |
| Alcohol, units/w | 0.5 (0–4) | 1 (0–4) | 0.5 (0–4) | 0 (0–4)a | .03 |
| SBP | 133.6 ± 18.6 | 131.8 ± 12.6 | 134.7 ± 18.8b | 135.5 ± 17.9a | <.001 |
| DBP | 81.8 ± 11.4 | 81.4 ± 11.4 | 82.3 ± 11.7 | 81.7 ± 10.9 | .07 |
| Sleep-disordered breathing | |||||
| AHI | 6.3 ± 4.3 | 2.2 ± 1.4 | 7.8 ± 1.7b | 12.8 ± 1.2a,c | <.001 |
| ODI | 4.4 (1.7–8.5) | 1.9 (0.7–3.7) | 6.4 (3.9–9.1)b | 10.3 (6.6–13.7)a,c | <.001 |
| Mean oxygen saturation | 94.5 (93.1–95.7) | 95 (93.6–96.0) | 94.1 (93.0–95.2)b | 94.1 (93.0–95.2)a | <.001 |
| Lowest oxygen saturation | 87 (83–90) | 89 (86–91) | 86 (82–88)b | 84 (81–88)a,c | <.001 |
| Daytime sleepiness | |||||
| ESS | 9.3 ± 5.2 | 9.3 ± 5.3 | 9.2 ± 5.0 | 9.3 ± 5.0 | .82 |
| ESS ≥ 10 | 2,129 (47%) | 947 (47%) | 773 (46%) | 409 (46%) | .86 |
| Comorbidities | |||||
| SAH | 1,878 (40%) | 610 (30%) | 784 (45%)b | 483 (52%)a,c | <.001 |
| Diabetes type 2 | 585 (12%) | 202 (10%) | 231 (13%)b | 152 (16%)a,c | <.001 |
| Hyperlipidemia | 951 (20%) | 338 (16%) | 379(22%)b | 234 (25%)a | <.001 |
| COPD | 297 (6%) | 131 (6%) | 108 (6%) | 58 (6%) | .98 |
| Coronary heart disease | 383 (8%) | 128 (6%) | 154 (9%)b | 101 (11%)a | <.001 |
| Cerebrovascular disease | 125 (3%) | 34 (2%) | 64 (4%)b | 27 (3%)a | <.001 |
| Atrial fibrillation | 110 (2%) | 37 (2%) | 37 (3%) | 26 (3%) | .11 |
Data are presented as mean values ± SD, median (25th–75th percentile), or n (%). aP < .05 mildAHI 11-<15/h vs nonapneic snorers. bP < .05 mildAHI 5-<11/h vs nonapneic snorers. cP < .05 patients with mildAHI 11-<15/h vs mildAHI 5-<11/h OSA. AHI = apnea-hypopnea index, BMI = body mass index, COPD = chronic obstructive pulmonary disease, DBP = diastolic blood pressure, ESS = Epworth sleepiness scale, HC = hip circumference, NC = neck circumference, ODI = oxygen desaturation index, SAH = systemic arterial hypertension, SBP = systolic blood pressure, WC = waist circumference.