Figure 4.

Inhibiting miR-20a and enhancing CDH1 attenuate pathological damage of neurons in brain tissues of rats with cerebral I/R injury. (a). HE staining of the pathological structure of neurons in hippocampus of rats; (b). HE staining of the pathological structure of neurons in the cortex of rats; (c). Nissl staining of Nissl bodies in the hippocampus of rat brain tissues; (d). Comparison of the number of Nissl bodies in the hippocampus of rat brain tissues (n = 3); (e). Nissl staining of the integrity of neurons in the cortex; (f). The number of intact neurons in the cortex of rat brain tissues (n = 3); a P < 0.05 compared with the sham group; b P < 0.05 compared with the inhibitor NC group; c P < 0.05 compared with the OE-NC group; d P < 0.05 compared with the miR-20a inhibitor + si-NC group; data were analyzed by one-way ANOVA while pairwise comparison after one-way ANOVA by Tukey’s multiple comparisons test