Table 3.

Pre-loss social network size predicting trajectories of immune function before and after bereavement

Effect	Response to Con A				Response to PHA
	b	SE	DF	p	b	SE	DF	p
Intercept	0.11*	0.038	106	0.005	0.27*	0.048	106	<.0001
Age	−0.0002	0.0013	46	0.893	−0.0034	0.0019	46	0.077
BMI	0.0004	0.0033	538	0.904	0.0053	0.0027	538	0.053
Comorbidities	0.0010	0.0021	534	0.629	−0.0024	0.0017	534	0.168
Female	−0.017	0.025	46.5	0.505	0.0044	0.036	46.5	0.902
Intercept spline	0.062*	0.028	536	0.029	0,022	0.014	536	0.365
Time since loss (pre-loss slope)	−0.096*	0.020	540	<.0001	−0.073*	0.016	540	<.0001
Slope spline	0.051*	0.021	537	0.015	0.016	0.018	537	0.368
Concentration 2.5 vs. 10.0	0.065*	0.019	530	0.001	−0.017	0.016	530	0.284
Concentration 5.0 vs. 10.0	0.060*	0.019	530	0.001	−0.013	0.016	530	0.420
Intercept spline * Conc. 2.5 v. 10.0	−0.029	0.023	530	0.202	0.011	0.019	530	0.578
Intercept spline * Conc. 5.0 v. 10.0	−0.017	0.023	530	0.457	0.012	0.019	530	0.542
Slope * Conc. 2.5 v. 10.0	−0.0035	0.015	530	0.821	−0.011	0.013	530	0.411
Slope * Conc. 5.0 v. 10.0	0.0009	0.015	530	0.952	−0.0061	0.013	530	0.636
Slope spline * Conc. 2.5 v. 10.0	0.014	0.017	530	0.397	0.016	0.014	530	0.256
Slope spline * Conc. 5.0 v. 10.0	0.0072	0.017	530	0.664	0.0076	0.014	530	0.584
Social network size	0.0013	0.0015	98.1	0.372	−0.0007	0.0019	98.1	0.728
Intercept spline * Social network size	−0.0037*	0.0011	536	0.001	−0.0006	0.0009	536	0.532
Slope * Social network size	0.0033*	0.0007	541	<.0001	0.0014*	0.0006	541	0.025
Slope spline * Social network size	−0.0018*	0.0008	537	0.019	−0.0004	0.0007	537	0.558

Note. Spline terms reflect changes in the intercept and time slope at the point of spousa loss. BMI = body mass index; Con A = Concanavalin A; PHA = phytohemagglutinin; Conc. = mitogen concentration.

^*p < .05. N_caregivers = 52