Table 6.

Cost-effectiveness, cost/QALY (£): mini-sternotomy versus conventional surgery

Model	Incremental cost (95% CI)	Incremental QALYs (95% CI)	ICER (95% CI)	P value*	P value†
Multiple imputation, covariate adjusted‡	508(−202 to 1217)	−0.007(−0.016 to 0.002)	Dominated§	0.058	0.052
Multiple imputation, unadjusted	859(−116 to 1833)	−0.008(−0.018 to 0.003)	Dominated	0.023	0.021
Complete case, covariate adjusted‡	630(25 to 1224)	−0.007(−0.016 to 0.002)	Dominated	0.013	0.011
Complete case, unadjusted	544(−99 to 1142)	−0.009(−0.02 to 0.002)	Dominated	0.027	0.022

*Probability cost-effective or net monetary benefit if willing to pay £20 000/QALY.

†Probability cost-effective or net monetary benefit if willing to pay £30 000/QALY.

‡Regression estimates adjusted for trial stratifying covariates and baseline EQ-5D.

§Dominance indicates average costs were less and average benefit greater for conventional surgery.