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. 2021 Jan 18;8:592008. doi: 10.3389/fbioe.2020.592008

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Copyright © 2021 Anastasio, Paniagua, Diamond, Ferlauto and Fernandez-Moure.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Representation of a 3D Bone Scaffold releasing nano-NO. The biologic benefits of NO on bone healing can be realized through incorporation of NO into a 3D bone scaffold and implantation of that scaffold into a fracture site. This figure was created using Servier Medical Art templates, which are licensed under a Creative Commons Attribution 3.0 Unported License (https://creativecommons.org/licenses/by-sa/3.0/legalcode); https://smart.servier.com.