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(A) Hematoxylin and eosin (H&E) staining of one of the gliomas included in the investigated cohort (case #1) revealing a pleomorphic astrocytic neoplasm with mitotic figures. (B) Immunohistochemical staining for histone H3 lysine 27 trimethylation (H3K27me3) showing a loss of nuclear expression in the tumor cells.
