Figure 2.

Mrp4 has no role in the regulation of hepatocyte proliferation during liver regeneration processes. A, Representative images of WT and Mrp4 KO liver sections stained for Ki-67 antigen (200× magnification. B, Quantification of Ki-67 staining. C, mRNA levels of 2 additional hepatocyte proliferation markers, cyclin D, and PCNA. D, Western blot images of PCNA and β-actin protein in total protein lysates. Data are presented as mean ± SEM (p ≤ .05). An asterisk “*” denotes significant difference between WT and Mrp4 KO mice.