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. 2021 Jan 18;115(1):53–60. doi: 10.1080/20477724.2020.1845479

Table 2.

MICs of chlorhexidine and isopropanol by antibiotics

Antimicrobial
agents
Chlorhexidine MIC (µg/mL)
p-value
Isopropanol MIC (mg/mL)
p-value
MIC50 MIC90 Range   MIC50 MIC90 Range  
Colistin                
Sensitive 32 64 8–128 0.329 64 128 16–256 0.609
Resistant 32 32 8–32   80 128 32–128  
Imipenem                
Sensitive 32 64 8–128 0.105 64 128 32–128 0.675
Resistant 32 128 8–128   64 128 16–256  
Meropenem                
Sensitive 32 64 8–128 0.158 64 128 32–256 0.647
Resistant 32 128 8–128   64 128 16–256  
PIP/TZB                
Sensitive 32 64 8–128 0.165 64 128 32–128 0.815
Resistant 32 128 8–128   64 128 16–128  
Chloramphenicol                
Sensitive 32 128 8–128 0.183 32 128 16–256 0.101
Resistant 16 64 32–256   64 128 32–256  
TMP/SMX                
Sensitive 16 64 8–128 0.039‡ 64 128 32–128 0.708
Resistant 32 128 8–128   64 128 16–256  
Nitrofurantoin                
Sensitive 32 64 8–64 0.875 48 128 16–128 0.610
Resistant 32 128 8–128   64 128 16–256  
Aztreonam                
Sensitive 32 64 8–128 0.598 32 128 32–256 0.510
Resistant 32 64 8–128   64 128 16–256  
Ciprofloxacin                
Sensitive 64 128 8–128 0.138 48 256 32–256 0.697
Resistant 32 64 8–128   64 128 16–256  
Levofloxacin                
Sensitive 32 128 8–128 0.059† 64 128 16–256 0.596
Resistant 16 64 8–128   64 128 32–128  
Cefotaxime                
Sensitive 32 128 8–128 0.979 64 128 32–256 0.991
Resistant 32 64 8–128   64 128 16–256  
Ceftazidime                
Sensitive 32 64 8–64 0.881 64 64 32–128 0.781
Resistant 32 128 8–128   64 128 16–256  
AMC                
Sensitive 16 64 8–128 0.266 64 256 32–256 0.199
Resistant 32 64 8–128   64 128 16–128  
Gentamicin                
Sensitive 32 64 8–128 0.115 64 128 32–256 0.586
Resistant 64 128 8–128   64 128 16–128  
Amikacin                
Sensitive -     NA -     NA
Resistant 32 64 8–128   64 128 16–256  

MIC, Minimal Inhibitory Concentration; Me, Median; IQR, Interquartile range; Pip/tzb, piperacillin/tazobactam; TMP/SMX, trimethoprim/sulfamethoxazole; AMC, amoxicillin/clavulanate; †, p value <0.10; ‡, p value <0.05