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. 2021 Jan 18;115(1):53–60. doi: 10.1080/20477724.2020.1845479

Table 3.

Regression analysis for log2(MIC) of chlorhexidine and isopropanol

Associated Factor Chlorhexidine MIC
(Log2µg/mL)
ß (95% CI)
p-value Isopropanol MIC
(Log2 mg/mL)
ß (95% CI)
p-value
Institution        
INMP Ref.   Ref  
HNGAI 0.66 (−0.01, 1.32) 0.054† −0.23 (−0.76, 0.29) 0.375
HN2M 0.53 (−0.31, 1.37) 0.210 −0.77 (−1.54, −0.01) 0.048‡
Fomites source −0.22 (−1.01, 0.58) 0.588 −0.22 (−1.01, 0.58) 0.588
PFGE Type 4 0.51 (−0.26, 1.28) 0.191 −0.11 (−0.63, 0.41) 0.680
Carbapenemases 0.66 (−0.06, 1.38) 0.072† −0.23 (−0.79, 0.32) 0.400
Colistin −0.56 (−1.68, 0.56) 0.321 0.29 (−0.67, 1.25) 0.543
Imipenem 0.52 (−0.09, 1.13) 0.094† −0.10 (−0.41, 0.61) 0.703
Meropenem 0.44 (−0.17, 1.06) 0.158 −0.15 (−0.66, 0.36) 0.547
PIP/TZB 0.45 (−0.16, 1.07) 0.147 −0.04 (−0.55, 0.48) 0.889
Chloramphenicol −0.46 (−1.14, 0.23) 0.186 0.43 (−0.12, 0.98) 0.122
TMP/SMX 0.65 (0.03, 1.27) 0.041‡ −0.07 (−0.59, 0.44) 0.779
Nitrofurantoin 0.09 (−0.55, 0.75) 0.764 0.16 (−0.37, 0.69) 0.547
Aztreonam −0.51 (−0.51, 0.81) 0.645 0.09 (−0.46, 0.63) 0.741
Ciprofloxacin −0.68 (−1.56, 0.21) 0.132 −0.32 (−1.11, 0.47) 0.422
Levofloxacin −0.60 (−1.23, 0.03) 0.061† 0.11 (−0.42, 0.64) 0.678
Cefotaxime −0.02 (−0.74, 0.69) 0.946 −0.07 (−0.66, 0.52) 0.814
Ceftazidime 0.07 (−0.66, 0.81) 0.840 −0.03 (−0.63, 0.58) 0.934
AMC 0.38 (−0.30, 1.05) 0.270 −0.49 (−1.03, 0.06) 0.078
Gentamicin 0.48 (−0.15, 1.11) 0.129 −0.25 (−0.77, 0.27) 0.339

MIC, Minimal Inhibitory Concentration; INMP, Instituto Nacional Materno Perinatal; HNGAI, Hospital Nacional Guillermo Almenara Irigoyen; HN2M, Hospital Nacional Dos de Mayo; PFGE, pulsed field gel electrophoresis; PIP/TZB, piperacillin/tazobactam; TMP/SMX, trimethoprim/sulfamethoxazole; AMC, amoxicillin/clavulanate; ß, linear regression coefficient; 95% CI, 95% confidence interval; †, p value <0.10; ‡, p value <0.05