Table 6.
Overall Comparative Diagnostic Performance of Three Different Commercial Available SARS-CoV-2 IgG/IgM Rapid Test Against RT-PCR, 2020, Addis Ababa, Ethiopia
| Manufacturer/Test Kit | Rate of Correct Positive Test Results (Percent Agreement with rt PCR) | Rate of Correct Negative Test Results (Percent Agreement with rtPCR) | Sensitivity (%), 95% CI | Specificity (%), 95% CI | Positive Predictive Value (%), 95% CI | Negative Predictive Value (%), 95% CI | Kappa Value*, 95% CI | ||
|---|---|---|---|---|---|---|---|---|---|
| Total =52/85 | |||||||||
| IgG&IgM | IgG | IgM | |||||||
| A | 31 | 12 | 9 | 111/115 | 61.18%(49.96–71.37%) | 97%(90.81–98.88%) | 92.9(81.9–97.7%) | 77.08%(69.19–83.49%) | 0.60(0.48–0.83), |
| B | Total =63/85 | 109/115 | 74.12% (63.28–82.74%) | 94.78%(88.52–97.86%) | 91.30%(81.39–96.42%) | 83.21%(75.45–88.95%) | 0.71 (0.65–0.93) | ||
| 29 | 22 | 12 | |||||||
| C | Total= 71/85 | 109/115 | 83.53% (73.57– 90.38%) | 94.78%(88.52–97.86%) | 92.21%(83.21–96.79%) | 88.62%(81.32–93.41%) | 0.80(0.76–1.04) | ||
| 16 | 33 | 22 | |||||||
Notes: A= EGENES, B= CTk onsite, C= ACON, *un-weighted kappa value.