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. 2021 Jan 25;43(1):291–301. doi: 10.1080/0886022X.2021.1871922

Figure 4.

Figure 4.

miR-34b-5p targets AQP2. Notes: (A) 3′UTR of AQP2 where miR-34b-5p binds to; (B) dual-luciferase reporter assay for verifying the targeting relationship between miR-34b-5p and AQP2; **P < 0.01, compared to the mimic NC + wt-AQP2 group. qRT-PCR (C) and Western blotting (D) detected the expression of AQP2 in LPS-induced HK-2 cells after transfection of miR-34b-5p inhibitor or miR-34b-5p mimic; *P < 0.05, **P < 0.01, compared to the LPS + inhibitor NC group or LPS + mimic NC group.