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. 2021 Feb 1;16(2):e0246311. doi: 10.1371/journal.pone.0246311

Table 1. Nondimensional parameter values used in this work unless indicated otherwise.

Parameter Meaning Value
Da Diffusion constant of active nucleators 4 ⋅ 10−2
va Effective actin polymerization speed 0.1–0.6
kd Effective filament degradation rate 176
ω Cooperative binding strength of nucleators 6 ⋅ 10−3
ωd Detachment rate of active nucleators 0.1 − 0.6
α Actin polymerization rate 588
ntot Average total nucleator density 700
L System length 1.3
Ng Number of grid points per dimension 256
ω0-1 Time scale 91.6 s
Di/ω0 Length scale 63.5 μm
DΨ Phasefield relaxation / surface tension coefficient 5 ⋅ 10−3
κ Phasefield timescale modifier 118
ϵ Area conservation strength 8
β Actin-membrane interaction coefficient 5.75 ⋅ 10−3
A0 Mean cell area 0.083

The length and time scales are chosen such that the ensuing dynamics is comparable to that of immature dendritic cells [10].