Fig 9. Induction of the oral inflammatory response by C. albicans invasins and candidalysin.

Levels of the indicated inflammatory mediators in the tongues of mice orally inoculated with the indicated strains of C. albicans after 1 d (A) and 2 d (B) of infection. Results are the median ± interquartile range of a total of 7 mice in each group from a single experiment. Median levels of inflammatory mediators in uninfected mice are indicated with dashed line if above 0. The data were analyzed by the Kruskal-Wallis test corrected for multiple comparisons. *, p < 0.05; **, p < 0.01; ***, p < 0.001.