Table 1.
Characteristics of the Study Patients (BZD Users: n=37 in 2004 and n=31 in 2015)
| All Study Patients | BZD Users | |||||||
|---|---|---|---|---|---|---|---|---|
| 2004 (n = 164) | 2015 (n = 105) | p | 2004 (n = 37) | 2015 (n = 31) | p | |||
| Gender n (%) | Female | 128 (78) | 64 (61) | – | 30 (81) | 25 (81) | – | |
| Male | 36 (22) | 41 (39) | – | 7 (19) | 6 (19) | – | ||
| Age (y) Mean ± SD | 81.6 ± 6.8 | 81.9 ± 8.1 | 0.767 | 80.3 ± 5.4 | 80.2 ± 8.6 | 0.951 | ||
| Number of total medication, Median [LQ, UQ] | All | 8 [6,12] | 12 [9,16] | <0.0001 | 10 [7,15] | 16 [12,18] | <0.001 | |
| Regular use | 7 [5,11] | 9 [6,11] | 0.007 | 8 [6,12] | 11 [7,12] | 0.664 | ||
| PRN use | 1 [0,2] | 3 [1,6] | <0.0001 | 1 [0,3] | 6 [4,6] | <0.001 | ||
| Use of at least one BZD n (%) | All | 76 (46) | 36 (34) | 0.05 | NE | NE | NE | |
| Regular use | 51 (31) | 13 (12) | <0.005 | 21 (57) | 10 (32) | 0.043 | ||
| PRN use | 36 (22) | 27 (26) | 0.477 | 17 (40) | 25 (81) | <0.005 | ||
| Concomitant use of BZD (two or three) n (%) | Regular or PRN or use | 20 (12) | 7 (7) | 0.110 | 11 (30) | 6 (19) | 0.132 | |
Abbreviations: BZD, benzodiazepines and related drugs; PRN use, pro re nata (when required); SD, standard deviation; LQ, lower quartile; UQ, upper quartile; NE, not estimable.