Figure 2.

The comparison of chest computed tomography (lung window). (A) Computed tomography on admission showed lung fibrosis, bilateral interstitial opacities, and thickened interlobular septa. (B) Computed tomography after initiation of macitentan 10 mg and tadalafil 20 mg showed lung fibrosis, bilateral interstitial opacities, and thickened interlobular septa same as that on admission. It newly revealed slight pulmonary oedema. (C) Computed tomography after administration of prednisone revealed some improvement in lung fibrosis, bilateral interstitial opacities, and thickened interlobular septa.