Table 1.
Clinical course and haemodynamics
| Baseline | 2 weeks after | 2 months after | 7 months after | |
|---|---|---|---|---|
| Therapies | Oxygen | Oxygen Macitentan 10 mg Tadalafil 20 mg | Oxygen Macitentan 10 mg Tadalafil 20 mg Prednisone | |
| Characteristics | ||||
| 6MWD (min) | 300 | 370 | 400 | |
| DLCO (% of predicted value) | 16.2 | 17.6 | 23.3 | |
| Haemodynamics | ||||
| Mean PAP (mmHg) | 43 | 35 | 27 | |
| Mean RAP (mmHg) | 1 | 3 | 1 | |
| PAWP (mmHg) | 15 | 15 | 7 | |
| Cardiac index (L/min/m2) | 1.96 | 3.21 | 2.56 | |
| PVR (WU) | 9.59 | 6.23 | 5.03 |
6MWD, 6-minute walk distance; DLCO, the diffusing capacity of the lungs for carbon monoxide; PAP, pulmonary artery pressure; PAWP, pulmonary artery wedge pressure; PVR, pulmonary vascular resistance; RAP, right atrium pressure.