Table 5.
Relationship between clinicopathological factors and the effectiveness of chemotherapy in patients with different methylation status.
| Chemotherapy efficacy | |||
| Noneffective (PD+SD) | effective (CR+PR) | P | |
| SYNE1 negative | |||
| Recurrence/ Palliative | |||
| Recurrence | 11 | 10 | .020 |
| Palliative | 24 | 2 | |
| SYNE1 positive | |||
| Pathological type | |||
| Simple adenocarcinoma | 13 | 0 | .044 |
| Other | 2 | 2 | |
| MAGI2 negative | |||
| Lymph node staging | |||
| N0-2 | 13 | 11 | .030 |
| N3 | 18 | 1 | |
CR = complete remission, MAGI2 = membrane-associated guanylate kinase protein 2, PD = disease progression, PR = partial remission, SD = stable disease, SYNE1 = nuclear envelop spectrin repeat protein, Nesprin1.