Table 1.

Predicted binding sites for transcription factors affected by the SNPs in Homo sapiens.

SNPs	Change mode	Transcription factors
g.233250963T>C (rs1816753)	create	TRPS1, SPDEF
	abolish	GLI2
g.233251039T>C (rs12476635)	create	AP-2
	abolish	BARX2, HOX, DLX
g.233251699T>G (rs2289477)	create	ZNF
	abolish	NFIB, CHURC1, HSF4

AP-2 = Integrase-type DNA-binding superfamily protein, BARX2 = BarH-like homeobox 2, CHURC1 = churchill domain containing 1, DLX = distal-less homeobox, GLI2 = GLI family zinc finger 2, HSF4 = heat shock transcription factor 4, NFIB = nuclear factor I B, SPDEF = SAM-pointed domain-containing Ets-like factor, TRPS1 = transcriptional repressor GATA binding 1, ZNF = zinc-finger.