Fig. 2.

Functional verification of AAV-5HRE-bFGF-DPSCs in vivo. (A) Immunofluorescence staining showing HIF-1α (green) and bFGF (red) in the Sham, SCI group, AAV-5HRE-DPSCs (CON-DPSCs) group and AAV-5HRE-bFGF-DPSCs (bFGF-DPSCs) group in 30 d.a.t. and bFGF-DPSCs group in 14 d.a.t.. The nucleus is labeled by DAPI (blue). Magnification: 40X; Scale: 50 μm. (B–C) The fluorescence intensity of HIF-1α and bFGF in the Sham, SCI group, CON-DPSCs group and bFGF-DPSCs group in 30 d.a.t.. (D–E) The fluorescence intensity of HIF-1α and bFGF in 14 and 30 d.a.t.. (F) The ratio of HIF-1α⁺ & bFGF⁺ cells in bFGF⁺ cells in 14 and 30 d.a.t.. * represents P < 0.05. ** represents P < 0.01. *** represents P < 0.001. n.s. represents no statistical significance. Data are represented as mean ± SD (n = 6). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)