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. 2021 Jan 30;6(8):2452–2466. doi: 10.1016/j.bioactmat.2021.01.024

Fig. 8.

Fig. 8

AAV-5HRE-bFGF-DPSCs promote the recovery of locomotion in SCI rats. (A) The BBB scores of the rats in the Sham, SCI group, AAV-5HRE-DPSCs (CON-DPSCs) group and AAV-5HRE-bFGF-DPSCs (bFGF-DPSCs) group. (B) The inclined plane test scores of rats in the Sham, SCI group, CON-DPSCs group and bFGF-DPSCs group. (C) Video sequences showing rats walk in 30 d.a.t. Accordingly, the weight support, leg extensor spasms, slow steps and foot placement were analyzed. Foot movement is highlighted by arrows. The initial position of the move is highlighted by red dots. Scale bar: 20 mm. (D) Weight support (quantified as the height of the trunk from the ground). (E) Foot error. (F) Spasm. (G) Single cycle advance distance. (H) Footprint analysis of Sham, SCI group, CON-DPSCs group and bFGF-DPSCs group in 30 d.a.t.. * represents P < 0.05. ** represents P < 0.01. *** represents P < 0.001. n.s. means no statistical significance. Data are represented as mean ± SD (n = 6). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)