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. 2021 Jan 19;11:640203. doi: 10.3389/fphar.2020.640203

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Copyright © 2021 Wang, Wang, Li, Wang, Shang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sepsis patients contain more HSPCs in the PB than healthy control subjects. (A,B) Representative fluorescence-activated plots of CD34⁺ cells in healthy controls (A) and sepsis patients (B). (C,D) Representative fluorescence-activated plots of CD34⁺CD38⁺ cells in healthy control (C) and sepsis patients (D). (E,F) Kinetic analysis of CD34⁺ cells (E) and CD34⁺CD38⁺ cells (F). HSPC, hematopoietic stem and progenitor cell; PB, peripheral blood; PBMC, peripheral blood mononuclear cells; SSC, dide scatter; C, healthy control; D1, sepsis on day 1; D4, sepsis on day 4; D7, sepsis on day 7. (*p < 0.05).