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. 2021 Jan 19;11:622046. doi: 10.3389/fphar.2020.622046

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Copyright © 2021 Zhang, Wang, Sheng, Huang, Tang, Ma and Hong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Emodin inhibited MCF-7 cell proliferation and growth. Cell morphology under different concentrations of emodin (B) MTT assays showed the effects of emodin on MCF-7 cell viability. Values represent mean ± SD, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control group (24 h); #p < 0.05, ##p < 0.01, ###p < 0.001 vs. control group (48 h); +p < 0.05, ++p < 0.01, +++p < 0.001 vs. control group (72 h) (C) MTT assays showed the effects of emodin containing 10 μmol/L of CH223191 on MCF-7 cell viability. Values represent mean ± SD, n = 3. *p < 0.05, **p < 0.01, ***p < 0.001 vs. control group (72 h).