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Binding affinities of IFN-I. (A) Equilibrium disassociation constants for the IFN-I. IFNα subtypes are from (63); IFNβ from (64), and IFNϵ, -κ, and -ω from (65). (B) Product of KD for IFNAR1 and IFNAR2, normalized to IFNα2. Highlighting and bar colors indicate conserved (blue) and variant subtypes (orange).
