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. 2021 Jan 19;11:599637. doi: 10.3389/fimmu.2020.599637

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Copyright © 2021 Smeekens, Johnson-Weaver, Hinton, Azcarate-Peril, Moran, Immormino, Kesselring, Steinbach, Orgel, Staats, Burks, Mucha, Ferris and Kulis

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gut microbiome changes after food protein exposure in CC027/GeniUnc (n = 7–10 per food) and C3H/HeJ (n = 7–8 per food) mice. (A) PCoA plot of compositional perturbation explaining 36.71% of total variation grouped by strain-food protein. (B) PCA biplot showing relative location of clusters and how the mean strain-food protein log-ratios within the perturbation signature contribute to differences between groups. (C) Depletion or enrichment of specific taxa relative to Listeria within each cluster. Error bars reflect 95% confidence intervals of the mean log-ratio value for all samples within each cluster. All taxa information is included in the following sequence: order, family, genus, species.