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PGC-1α is required for PKM2 activation-induced endotoxin tolerance. (A, B) Supernatant TNF-α and IL-6 levels in control RAW264.7 cells or PGC-1α knockdown RAW264.7 cells stimulated with LPS and/or TEPP-46 were measured using ELISA (n=3). *p < 0.05, **p < 0.01.
