Table 1.

The interaction of surfactant proteins A (SP-A) and SP-D with host cell surface proteins, soluble proteins, and receptors.

Protein	Target Cell/Function	Collectin	Reference
SPR-210 (Myosin 18A/CD245)	Monocytes, macrophages, T-cells, type II epithelial cells	SP-A	(53–57)
CD14	Myeloid lineage cells	SP-A and SP-D	(58, 59)
DC-SIGN	Macrophages and dendritic cells	SP-D	(60)
Calrecticulin/CD91	Macrophages, neutrophils	SP-A and SP-D	(61, 62)
CD93 (C1qRp)	Endothelial cells, platelets, neutrophils, monocytes, microglial cells, monocytes	SP-A	(63, 64)
CR1	B cells, monocytes, neutrophils, monocytes, microglial cells	SP-A	(65)
SIRPα	Myeloid lineage cells	SP-A and SP-D	(61, 66, 67)
SIRPβ	Myeloid lineage cells	SP-D	(67)
Osteoclast-Associated Receptor (OSCAR)	CCR2+ monocytes	SP-D	(68)
NKp46	NK cells	SP-D	(69)
leukocyte‐associated Ig‐like receptreceptor‐1/2 (LAIR 1/2)	T cells	SP-D	(70)
Fc Receptor γII (FcγRII/CD32)	Eosinophils	SP-D	(71)
TLR2, TLR4 and MD-2	Myeloid lineage cells	SP-A and SP-D	(72–75)
CR3 (CD11b/CD18)	Macrophages	SP-A	(76, 77)
Ig-Hepta (GPR116)	Type II cells	SP-D	(78)
Uroplakin Ia	Bladder epithelial cells	SP-D	(79)
Epidermal Growth Factor Receptor (EGFR)	Human lung adenocarcinoma epithelial cell lines	SP-D	(80)
Gp 340	Macrophages	SP-A and SP-D	(81, 82)
MPO	Neutrophils	SP-A and SP-D	(83)
C1q	Macrophages	SP-A	(84, 85)
Immunoglobulins	Soluble	SP-A and SP-D	(86, 87)
Defensins	Soluble	SP-D	(88, 89)
Decorin	Soluble	SP-D	(90)