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. 2021 Jan 19;11:543627. doi: 10.3389/fendo.2020.543627

Table 2.

The characteristics of all including trials.

Reference Location(Language) Sample size Mean age or age range Disease duration Intervention Group time/per week/duration Control group Outcome measure Attrition AE Main findings (p value of intergroup/intragroup difference)
Shen XY et al. (48) China
(Chinese)
TG: 54
CG: 54
TG: 67.8 ± 5.1 CG: 66.2 ± 4.6 TG: 9.6 ± 6.8 y
CG: 7.6 ± 5.9 y
24 form Tai Chi
60 min/3/12 weeks
Walking
60 min/3/12 weeks
DSQOL TG: 2
CG: 5
NR DAQOL: TG showed significant improvement in DAQOL compared to CG(p<0.05).
Wu F et al. (46) China
(Chinese)
TG: 20
CG: 20
TG: 51.3 ± 7.9 CG: 52.4 ± 5.5 TG: 1.35 ± 0.62 y
CG: 1.36 ± 0.71 y
24 form Tai Chi
60 min/3/24 weeks
No intervention SF-36 NR NR SF-36: TG showed significant improvements in PF/RP/GH/RE/SF/MH compared to CG (p<0.05).
Lam P et al. (44) Australia
(English)
TG: 28
CG: 25
TG: 63.2 ± 8.6 CG: 60.7 ± 12.2 > 6 m Yang and Sun style 20 form Tai Chi 60 min/3/12 weeks;
60 min/1/further 12 weeks
Wait list SF-36 TG: 7
CG: 3
NR SF-36: TG showed significant improvements in PF/SF/GH from baseline to post-treatment (all p<0.05). No significant difference in all SF-36 domains between two groups (p>0.05).
Li ZB et al. (34) China
(Chinese)
TG: 54
CG(a): 54
CG(b): 54 CG(c): 54
TG: 54.21 ± 9.47
CG(a): 50.42 ± 9.68
CG(b): 51.62 ± 7.83 CG(c): 52.69 ± 8.37
TG: 83.42 ± 43.52 m
CG(a): 72.18 ± 39.57 m
CG(b): 75.74 ± 42.39 m CG(c): 86.65 ± 49.72 m
24 form Tai Chi
30 min/7/12 weeks
CG(a): Baduanjin
CG(b): Aerobic Exercise
(brisk walking. etc)
CG(c): No intervention
BMI TG: 11
CG(a): 4 CG(b): 6 CG(c): 10
NR BMI: TG showed significant improvement in BMI from baseline to post-treatment (p<0.05).
Intergroup comparison was NR.
Meng E (49) China
(Chinese)
TG: 100
CG: 100
68. ± 3.2 2-23 y Tai Chi
3 months
Wait list SF-36 NR NR SF-36: TG showed significant improvement in GH and SF-36 total score compared to CG (p<0.05).
Wang P et al. (47) China
(Chinese)
TG: 34
CG: 30
TG: 48.24 ± 10.06 CG: 47.86 ± 11.12 TG: 1-18 y
CG: 1-17 y
24 form Tai Chi
45–60 min/5-7/24 weeks
No intervention SF-36 NR NR SF-36: TG showed significant improvement in RE (P<0.01), PF/RP/BP/GH/VT/SF (p<0.05), and SF-36 total score/PCS/MCS (p<0.01) compared to CG.
Wei DL et al. (33) China
(Chinese)
TG: 26
CG: 26
56.0 ± 7.2 0.5-3 y Tai Chi ball 36 form
60 min/6/12 weeks
Usual care BMI;
WHR
NR NR BMI/WHR: TG showed significant improvement in BMI/WHR from baseline to post-treatment(p<0.05). Intergroup comparison was NR.
Ahn S (40) South Korea
(English)
TG: 30
CG: 29
TG: 66.05 ± 6.42
CG: 62.73 ± 7.53
TG: 12.30 ± 8.81 y
CG: 13.00 ± 10.03 y
Tai Chi
60 min/2/12 weeks
Usual care SF-36 TG: 10
CG: 10
NR SF-36: TG showed significant improvement in PF/BP/RP/RE/SF compared to CG (p<0.05).
No significant difference in SF-36 subcomponents (PCS/MCS) between two groups (p>0.05).
Chen SC et al. (32) China
(English)
TG: 62
CG: 55
TG: 59.1 ± 6.2
CG: 57.4 ± 5.8
TG: 8.5 ± 3.5 y
CG: 7.8 ± 3.1 y
Chen style 99 form Tai Chi
60 min/3/12 weeks
Aerobic dancing
60 min/3/12 weeks
BMI TG: 6
CG: 7
NR BMI: TG showed significant improvement in BMI compared to CG (p=0.017).
Trang T et al. (35) Australia
(English)
TG: 18
CG: 20
TG: 60 ± 8
CG: 65 ± 8
TG: 8.5 y
CG: 9.0 y
Yang and Sun style Tai Chi, 60 min/2/12 weeks Sham exercise SF-36 TG: 1 Y SF-36: TG showed significant improvement in SF compared to CG (p=0.04).
Cai H (42) China
(Chinese)
TG: 27
CG: 28
TG: 65.54
CG: 64.51
TG: 4.93 y
CG: 5.44 y
Tai Chi
30 min/3/12 weeks
Wait list BMI CG:5 NR BMI: TG showed significant improvement in BMI compared to CG (p=0.004).
Chen ZC (52) China
(Chinese)
TG: 30
CG: 30
TG: 60.71 ± 7.06
CG: 61.14 ± 5.27
TG: 5.58 ± 2.77 y
CG: 6.00 ± 2.58 y
Tai Chi stick
60 min/4/12 weeks
No intervention BMI; WHR;
SF-36
TG: 2 NR BMI/WHR: TG showed significant improvement in BMI/WHR from baseline to post-treatment(p<0.05).
SF-36: TG showed significant improvement in all SF-36 domains compared to CG (all p<0.05).
Li HC et al. (50) China
(Chinese)
TG: 50
CG: 50
TG: 62.91 ± 2.48
CG: 63.27 ± 2.86
TG: 7.83 ± 2.16 y
CG: 8.14 ± 3.19 y
Chen style Tai Chi
40–50 min/7/24 weeks
Aerobic Exercise BMI;
WHR
NR NR BMI/WHR: No significant difference in BMI and WHR between two groups (p>0.05).
Bao QW et al. (53) China
(Chinese)
TG: 58
CG: 49
TG: 60.4 ± 6.9
CG: 68.4 ± 7.1
NR Tai Chi + standard diabetic care
120 min/14/24 weeks
Standard diabetic care BMI;
WHR
NR NR BMI/WHR: TG showed significant improvement in BMI and WHR compared to CG (p<0.05).
Zhao G et al. (45) China
(Chinese)
TG: 8
CG: 8
TG: 54.75 ± 6.09
CG: 52.38 ± 7.65
NR Chen style
60 min/7/16 weeks
No intervention BMI NR NR BMI: No significant difference in BMI between two groups (p>0.05).
Youngwan-chsetha S et al. (43) Thailand
(English)
TG: 34
CG: 35
TG: 60.71 ± 7.06
CG: 61.14 ± 5.27
TG: 2.47 ± 1.24 y
CG: 2.78 ± 1.18 y
Lin Housheng style Tai Chi + standard diabetic care 50 min/5/12 weeks Standard diabetic care BMI TG: 2
CG: 3
NR BMI: No significant difference in BMI between two groups (p=0.10).
Kan Y et al. (51) China
(Chinese)
TG: 26
CG: 22
52 ± 6.7 >3 y 24 form Tai Chi
60 min/7/12 weeks
Aerobic Exercise BMI NR NR BMI: TG showed significant improvement in BMI compared to CG (p<0.05).
Wang JH et al. (41) China
(Chinese)
TG: 10
CG: 6
60–70 >2 y 24 form Tai Chi
60 min/7/12 weeks
Aerobic Exercise BMI NR NR BMI: TG showed significant improvement in BMI compared to CG (p<0.05).

TG, Tai Chi Group; CG, control group; AE, adverse events; y, year; m, month; DSQOL, diabetes-specific quality of life; SF-36, Medical Outcomes Study Short Form-36; BMI, body mass index; WHR, waist-hip ratio; NR, not reported; SF-36 domains (PF, physical functioning; RP, role-physical; BP, bodily pain; GH, general health; VT, vitality; SF, social functioning; RE, role-emotional; MH, mental health; PCS, physical component summary, MCS=mental component summary).