Table 2.

SGK1 inhibitors and their various anti-tumor effects.

Molecule	Anti-tumor effects	References
GSK650394	Inducing apoptosis and cell cycle arrest; impairing invasion and migration	[19, 20, 49]
EMD638683	Inducing apoptosis and impairing migration	[30, 140, 143]
SI113	Inducing ER stress and apoptosis; inhibiting EMT	[24, 67, 141]
QGY-5-114-A	Inducing apoptosis and cell cycle arrest; impairing migration	[72]
ZINC00319000	Unclear, it needs to be further investigated	[142]

EMT, epithelial-to-mesenchymal transition; ER stress, endoplasmic reticulum stress.