Table 2.
Baseline characteristics and hormonal profiles according to ovarian hyperstimulation syndrome (OHSS) severity in women with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI).
| Variables | Mild OHSS | Moderate OHSS | P value |
|---|---|---|---|
| Number of patients | 128 | 527 | |
| Age* | 29.42 ± 3.53 | 28.41 ± 3.59 | 0.0027 |
| Weight | 61.89 ± 10.17 | 62.05 ± 9.83 | 0.7585 |
| BMI | 23.90 ± 3.76 | 23.65 ± 3.46 | 0.6651 |
| Duration of infertility | 4.54 ± 2.41 | 4.16 ± 2.04 | 0.2414 |
| Antral follicular count | 22.80 ± 2.84 | 23.13 ± 2.42 | 0.056 |
| Baseline hormone levels | |||
| FSH (mIU/ml)* | 5.89 ± 1.42 | 5.48 ± 1.27 | 0.0026 |
| E2 (pg/ml)* | 38.05 ± 30.90 | 45.40 ± 29.61 | <0.0001 |
| P4 (ng/ml) | 0.74 ± 0.73 | 0.77 ± 0.70 | 0.3422 |
| PRL (ng/ml) | 20.92 ± 29.50 | 19.95 ± 23.97 | 0.8363 |
| LH (mIU/ml) | 9.25 ± 6.07 | 9.03 ± 5.40 | 0.7007 |
| T* | 0.34 ± 0.14 | 0.38 ± 0.14 | 0.01 |
| Type of infertility | |||
| Secondary infertility | 42 (32.81) | 165 (31.31) | 0.74283 |
| Primary infertility | 86 (67.19) | 362 (68.69) | |
| Treatment | |||
| ICSI | 21 (16.41) | 84 (15.94) | 0.89723 |
| IVF | 107 (83.59) | 443 (84.06) | |
| Proposal type | |||
| Follicular phase long-acting protocol*# | 62 (48.44) | 388 (73.62) | <0.0001 |
| Long-acting protocol# | 66 (51.56) | 139 (26.38) |
*P < 0.05.
Data are mean ± standard deviation or N (% of response group). FSH, follicle-stimulating hormone; E2, estradiol; P4, progesterone; LH, luteinizing hormone; PRL, pituitary prolactin; T, testosterone; BMI, body mass index.
#They are both long agonist protocols, the difference between them is that the time of agonist-using, the former one is in the follicular phase, while the latter one is in the luteal phase.