Table 2.

LENT-SOMA grade 3–4 bladder or rectum toxicity after the end of treatment by fractionation groups

	64 Gy in 32 fractions (n=278)	55 Gy in 20 fractions (n=295)
2-year late toxicity
Rectum	7 (3%)	17 (6%)
Bladder	66 (24%)	74 (25%)
Rectum or bladder	69 (25%)*	82 (28%)†
5-year late toxicity
Rectum	8 (3%)	21 (7%)
Bladder	86 (31%)	88 (30%)
Rectum or bladder	89 (32%)‡	97 (33%)§

LENT-SOMA urinary and rectal dysfunction subscales were recorded up to 5 years after radiotherapy in the BC2001 and BCON trials. LENT-SOMA=Late Effects Normal Tissue Task Force-Subjective, Objective, Management, Analytic.

^*Four patients with both.

^†Nine patients with both.

^‡Five patients with both.

^§12 patients with both.