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. 2020 Oct 26;124(3):595–603. doi: 10.1038/s41416-020-01138-3

Fig. 3. PD-L1 expression is upregulated by Tmab in HER2-amplified GC cells directly co-cultured with NK cells.

Fig. 3

a PD-L1 expression on HER2-amplified GC cell lines (NCI-N87 and NUGC4) that were monocultured or co-cultured with NK cells, and treated with Tmab or hIgG (5 μg/ml) for 48 h. b PD-L1 expression on the GC cell lines that were monocultured or indirect co-cultured with NK cells, and treated with Tmab or hIgG. c PD-L1 expression on the GC cell lines that were monocultured or co-cultured with monocytes, and treated with Tmab or hIgG. PD-L1 expression were measured by multicolour flow cytometry. The data are represented by histograms and MFI values. NS, no significant difference. *P < 0.05.