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. 2021 Feb 1;11:2719. doi: 10.1038/s41598-021-81648-z

Table 1.

Characteristics of young male and female adult participants with mitral valve prolapse and those without.

Total (n = 2442) Males (n = 254) Females (n = 288)
MVP (−)
(n = 2360)
MVP (+)
(n = 82)
p-value MVP (−)
(n = 2077)
MVP (+)
(n = 77)
p-value MVP (−)
(n = 283)
MVP (+)
(n = 5)
p-value
Age 27.36 ± 5.62 26.51 ± 5.82 0.18 27.51 ± 5.70 26.48 ± 5.89 0.12 26.29 ± 4.88 27.00 ± 5.15 0.74
Height (cm) 170.78 ± 6.75 171.58 ± 5.97 0.28 172.12 ± 5.79 172.34 ± 5.19 0.74 160.93 ± 4.90 159.98 ± 5.50 0.66
Weight (kg) 72.12 ± 12.79 70.17 ± 11.68 0.17 73.83 ± 12.24 71.11 ± 11.38 0.05 59.52 ± 9.27 55.66 ± 4.75 0.35
Body mass index (kg/m2) 24.65 ± 3.69 23.78 ± 3.43 0.03 24.89 ± 3.70 23.91 ± 3.45 0.02 22.94 ± 3.16 21.81 ± 2.53 0.42
Body surface area (m2) 1.84 ± 0.19 1.82 ± 0.17 0.33 1.87 ± 0.17 1.84 ± 0.16 0.09 1.62 ± 0.14 1.57 ± 0.07 0.37
Waist circumference (cm) 82.57 ± 9.99 81.08 ± 10.03 0.18 83.59 ± 9.80 81.51 ± 10.05 0.06 75.10 ± 8.04 74.40 ± 7.47 0.84
Systolic blood pressure (mm Hg) 118.07 ± 13.72 116.50 ± 15.64 0.31 119.65 ± 13.30 117.32 ± 15.43 0.13 106.41 ± 10.90 103.80 ± 14.62 0.59
Diastolic blood pressure (mm Hg) 70.04 ± 10.40 70.03 ± 12.02 0.97 70.78 ± 10.43 71.01 ± 11.35 0.85 64.52 ± 8.31 54.40 ± 12.44 < 0.01
Heart rate (beats/minute) 66.72 ± 10.83 65.44 ± 10.87 0.29 66.53 ± 10.89 65.44 ± 11.09 0.39 68.17 ± 10.26 65.40 ± 7.40 0.54
Somatic symptoms 116 [4.9] 9 [11.0] 0.02 96 [4.6] 7 [9.1] 0.07 20 [7.0] 2 [40.0] 0.06
Pectus excavatum 13 [0.6] 7 [8.5] < 0.01 12 [0.6] 6 [7.8] < 0.01 1 [0.4] 1 [20.0] < 0.01
Current alcohol intake 1048 [44.4] 43 [52.4] 0.15 995 [47.9] 43 [55.8] 0.17 53 [18.7] 0 [0.0] 0.28
Current cigarette smoking 967 [41.0] 30 [36.6] 0.42 912 [43.9] 30 [39.0] 0.39 55 [19.4] 0 [0.0] 0.27
Serum creatinine (mg/dL) 0.92 ± 0.14 0.94 ± 0.13 0.36 0.96 ± 0.12 0.96 ± 0.12 0.98 0.68 ± 0.09 0.66 ± 0.06 0.51
Total cholesterol (mg/dL) 171.00 ± 33.36 167.43 ± 29.08 0.33 171.62 ± 33.87 167.56 ± 29.76 0.29 166.40 ± 29.02 165.40 ± 17.01 0.93
HDL-C (mg/dL) 49.78 ± 10.69 50.50 ± 10.60 0.54 48.57 ± 9.97 50.12 ± 10.80 0.18 58.67 ± 11.61 56.40 ± 3.78 0.66
LDL-C (mg/dL) 103.85 ± 28.93 99.71 ± 25.83 0.20 105.49 ± 29.23 100.13 ± 26.34 0.11 91.80 ± 23.33 93.20 ± 16.56 0.89
Serum triglyceride (mg/dL) 104.01 ± 84.10 91.16 ± 56.49 0.17 108.95 ± 87.48 91.86 ± 57.46 0.08 67.69 ± 36.24 80.40 ± 41.72 0.43
Fasting plasma glucose (mg/dL) 93.63 ± 11.89 90.30 ± 9.76 0.01 94.01 ± 12.34 90.25 ± 9.77 < 0.01 90.85 ± 7.22 91.20 ± 10.52 0.91
Hemoglobin (g/dL) 14.97 ± 1.25 15.12 ± 1.24 0.28 15.25 ± 0.96 15.28 ± 0.80 0.82 12.87 ± 1.10 12.62 ± 1.11 0.61

Continuous variables are expressed as mean ± SD (standard deviation), and categorical variables as N [%].

HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, MVP mitral valve prolapse.