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. 2020 Oct 27;124(3):658–662. doi: 10.1038/s41416-020-01131-w

Table 2.

Crudea- and multivariateb adjusted hazard ratio (HR) estimates for lung cancer with 95% confidence intervals (CIs) for different measures of smoking exposures, the Norwegian Women and Cancer Study, 1991–2015.

Smoking exposures Cases (n) HRa (95% CI) HRb (95% CI)
Neverc 43 1.00 (ref) 1.00 (ref)
Passive 53 1.33 (0.89–2.01) 1.34 (0.89–2.01)
Former 348 3.81 (2.77–5.23) 3.69 (2.68–5.09)
Current 1139 15.44 (11.37–20.98) 13.88 (10.18–18.91)
Ever 1464 7.67 (5.66–10.41) 6.80 (5.00–9.24)
Smoking duration in ever smokersd
 1–9 231 4.58 (3.29–6.39) 4.16 (2.98–5.82)
 10–19 203 4.24 (3.05–5.91) 4.22 (3.02–5.90)
 20–29 429 9.26 (6.75–12.71) 8.55 (6.20–11.77)
 ≥30 595 18.11 (13.25–24.74) 16.48 (12.02–22.60)
 P-trende <0.001 <0.001
Cigarettes smoked per day in ever smokersd
 1–9 376 4.46 (3.57–5.58) 4.28 (3.42–5.37)
 10–19 767 13.16 (10.65–16.28) 12.17 (9.81–15.10)
 >20 125 23.07 (17.70–30.06) 21.66 (16.54–28.37)
 P-trende <0.001 <0.001
Pack-years in ever smokersd
 1–5 199 4.01 (2.89–5.57) 3.81 (2.73–5.31)
 6–15 429 8.40 (6.13–11.50) 7.90 (5.74–10.86)
 >15 671 22.52 (16.53–30.69) 21.24 (15.52–29.06)
 P-trende <0.001 <0.001
Age at smoking initiation in ever smokersd
 >20 334 6.33 (4.84–7.62) 5.76 (4.55–7.28)
 17–20 739 9.95 (8.04–12.31) 9.08 (7.31–11.27)
 ≤17 315 6.07 (4.84–7.61) 5.70 (4.53–7.17)
 P-trende <0.001 <0.001

aAdjusted for age.

bAdjusted for age, duration of education and alcohol consumption, all at enrolment.

cNever-active, never-passive smokers as reference group.

dThe sum of cases in each interval in smoking duration, cigarettes day, pack-years and age at smoking initiation does not sum up to the total number of cases in ever smokers because of missing values.

eTest for trend excluding never smokers.